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NCT03723694 · ClinicalTrials.gov registry record · NA

Dietary Modulation of Neuroinflammation in Age-Related Memory Disorders

A NA study, sponsored by Columbia University.

Completed
Registry status
NA
Development phase
259
Enrollment target

NCT03723694: Completed NA study, sponsored by Columbia University.

NCT03723694 is a NA study that has completed, run by Columbia University. The registered enrollment target is 259 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03723694, a NA study, has completed, sponsored by Columbia University.

COMPLETED
Registry status
NA
Development phase
259 participants
Enrollment target

Study Summary

The purpose of this study is to test the effect of a cocoa-derived dietary flavanol on brain structures and cognitive outcomes in a 12-week randomized controlled trial of 146 healthy participants, age 50-69, who will receive this cocoa derivative or a placebo. Th investigators will also examine the role of inflammation in this relationship.

Primary Outcome

circulating levels of the inflammatory marker HMGB1

Interventions

  • DIETARY_SUPPLEMENT 650 mg of Cocoapro flavanols
  • DIETARY_SUPPLEMENT 0 mg of Cocoapro flavanols

Trial Details

FieldValue
Enrollment Target 259 participants
Start Date 2019-01-01
Est. Completion 2023-06-26
Phase NA
Columbia University

958 total trials

What the finished NCT03723694 record still lists

NCT03723694 is an interventional study that assigns participants to a tested intervention. The registered 259 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower).

The record links to 0 conditions, and to 2 interventions - of which 650 mg of Cocoapro flavanols is the first listed.

NCT03723694 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03723694 about?

NCT03723694 is a clinical study titled "Dietary Modulation of Neuroinflammation in Age-Related Memory Disorders". The purpose of this study is to test the effect of a cocoa-derived dietary flavanol on brain structures and cognitive outcomes in a 12-week randomized controlled trial of 146 healthy participants, age 50-69, who will receive this cocoa derivative or a placebo. Th investigators will also examine the ...

What is the current status of trial NCT03723694?

This trial is currently completed. It is a NA study. The enrollment target is 259 participants. The study started on 2019-01-01. Estimated completion is 2023-06-26.

What interventions are being tested in trial NCT03723694?

The interventions under investigation include: 650 mg of Cocoapro flavanols (DIETARY_SUPPLEMENT), 0 mg of Cocoapro flavanols (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT03723694?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03723694's enrollment target sits among peer trials

259 400th of 2000 higher than 1,599 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03723694, the US trial registry maintained by the National Library of Medicine. NCT03723694 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.