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NCT03716427 · ClinicalTrials.gov registry record · Phase 1
Drug Interaction Study of CT1812 in Healthy Volunteers
A Phase 1 study, sponsored by Cognition Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT03716427: Completed Phase 1 study, sponsored by Cognition Therapeutics.
NCT03716427 is a Phase 1 study that has completed, run by Cognition Therapeutics. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03716427, a Phase 1 study, has completed, sponsored by Cognition Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
This is Phase 1, single-center, open-label, single-sequence drug-drug interaction study to determine the effect of CT1812 (560 mg) once daily on the pharmacokinetics of 4 probe drugs (tolbutamide, midazolam, dextromethorphan and omeprazole).
Primary Outcome
Single dose (Day -2 and Day 6) pharmacokinetic parameter Area under the plasma-concentration time curve
Interventions
- DRUG Omeprazole
- DRUG midazolam
- DRUG CT1812
- DRUG dextromethorphan
- DRUG tolbutamide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2016-11-10 |
| Est. Completion | 2017-02-15 |
| Phase | Phase 1 |
What the finished NCT03716427 record still lists
NCT03716427 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 5 interventions - of which Omeprazole is the first listed.
NCT03716427 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03716427 about?
NCT03716427 is a clinical study titled "Drug Interaction Study of CT1812 in Healthy Volunteers". This is Phase 1, single-center, open-label, single-sequence drug-drug interaction study to determine the effect of CT1812 (560 mg) once daily on the pharmacokinetics of 4 probe drugs (tolbutamide, midazolam, dextromethorphan and omeprazole).
What is the current status of trial NCT03716427?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2016-11-10. Estimated completion is 2017-02-15.
What interventions are being tested in trial NCT03716427?
The interventions under investigation include: Omeprazole (DRUG), midazolam (DRUG), CT1812 (DRUG), dextromethorphan (DRUG), tolbutamide (DRUG).
Who is sponsoring clinical trial NCT03716427?
This trial is sponsored by Cognition Therapeutics, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03716427's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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