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NCT03715283 · ClinicalTrials.gov registry record · NA
Change in MUNIX in Patients With CMT1A Undergoing a Home Ankle Strengthening Program Versus Standard of Care
A NA study, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 19
- Enrollment target
NCT03715283 is a NA study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 19 participants.
The verdict
NCT03715283, a NA study, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 19 participants
- Enrollment target
Study Summary
Here the investigators aim to show that a focused lower extremity resistance strength training program in patients with Charcot-Marie-Tooth disease (CMT) results in increased motor strength of ankle plantar- and dorsi-flexion. The investigators will use motor unit index MUNIX and hand held dynamometry to correlate strength changes. The investigators believe that increased strength will correlate with an increased motor unit number and as such will prove that axonal renervation or improved recruitment is possible with a focused exercises in patients with CMT. Additionally, the investigators will show that that MUNIX declines over a 12-week period in patients with CMT whom continue standard of care. This will identify MUNIX as a responsive marker for disease progression in addition to detecting functional improvement, which will be valuable for future clinical trials.
Interventions
- OTHER Standard of Care
- OTHER Home Ankle Strengthing Program
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2019-01-15 |
| Est. Completion | 2019-09-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03715283
The ClinicalTrials.gov registry entry for NCT03715283 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Standard of Care is the first listed.
NCT03715283 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03715283 about?
NCT03715283 is a clinical study titled "Change in MUNIX in Patients With CMT1A Undergoing a Home Ankle Strengthening Program Versus Standard of Care". Here the investigators aim to show that a focused lower extremity resistance strength training program in patients with Charcot-Marie-Tooth disease (CMT) results in increased motor strength of ankle plantar- and dorsi-flexion. The investigators will use motor unit index MUNIX and hand held dynamomet...
What is the current status of trial NCT03715283?
This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2019-01-15. Estimated completion is 2019-09-01.
What interventions are being tested in trial NCT03715283?
The interventions under investigation include: Standard of Care (OTHER), Home Ankle Strengthing Program (OTHER).
Who is sponsoring clinical trial NCT03715283?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
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