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NCT03714880 · ClinicalTrials.gov registry record · Phase 2

Cervical Preparation With Mifepristone Prior to Osmotic Dilators

A Phase 2 study, sponsored by University of California, Davis.

Terminated
Registry status
Phase 2
Development phase
44
Enrollment target

NCT03714880: Clinical Trial Phase 2 study, sponsored by University of California, Davis.

NCT03714880 is a Phase 2 study that was terminated before completion, run by University of California, Davis. The registered enrollment target is 44 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03714880, a Phase 2 study, was terminated before completion, sponsored by University of California, Davis.

TERMINATED
Registry status
Phase 2
Development phase
44 participants
Enrollment target

Study Summary

The investigators plan to study the role of mifepristone prior to the placement of cervical osmotic dilators to evaluate if the medication helps increase the number of dilators. This may help improve safety of dilation and evacuation (D\&E) procedures.

Primary Outcome

The number of expected dilators (Dilapan-S) is calculated based on the gestational age. Four dilators are expected to be placed at 18 weeks 0 days to 19 weeks 6 days gestation. Five dilators are expected to be placed at 20 weeks 0 days to 20 weeks 6 days gestation. Six dilators are expected to be placed at 21 weeks 0 days to 21 weeks 6 days gestation. Seven dilators are expected to be placed at 22 weeks 0 days to 23 weeks 5 days gestation. Therefore, at any given gestational age, if the expected

Interventions

  • DRUG Placebo Oral Tablet
  • DRUG Mifepristone 200 MG

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2019-04-26
Est. Completion 2021-02-26
Phase Phase 2
University of California, Davis

657 total trials

Why NCT03714880 stopped before completion

NCT03714880 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo Oral Tablet is the first listed.

NCT03714880 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03714880 about?

NCT03714880 is a clinical study titled "Cervical Preparation With Mifepristone Prior to Osmotic Dilators". The investigators plan to study the role of mifepristone prior to the placement of cervical osmotic dilators to evaluate if the medication helps increase the number of dilators. This may help improve safety of dilation and evacuation (D\&E) procedures.

What is the current status of trial NCT03714880?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2019-04-26. Estimated completion is 2021-02-26.

What interventions are being tested in trial NCT03714880?

The interventions under investigation include: Placebo Oral Tablet (DRUG), Mifepristone 200 MG (DRUG).

Who is sponsoring clinical trial NCT03714880?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03714880's enrollment target sits among peer trials

44 1322nd of 2000 higher than 669 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03714880, the US trial registry maintained by the National Library of Medicine. NCT03714880 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.