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NCT03709927 · ClinicalTrials.gov registry record · Phase 1
4-way Crossover QT Evaluation in Healthy Subjects
A Phase 1 study, sponsored by Nabriva Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 41
- Enrollment target
NCT03709927: Completed Phase 1 study, sponsored by Nabriva Therapeutics.
NCT03709927 is a Phase 1 study that has completed, run by Nabriva Therapeutics. The registered enrollment target is 41 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03709927, a Phase 1 study, has completed, sponsored by Nabriva Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 41 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate if ZTI-01 (fosfomycin for injection), an investigational drug being developed to treat people with complicated urinary tract and kidney infections, has any effect on the electrical activity of the heart.
Primary Outcome
Determine the change-from-baseline QTc (ΔQTc) when compared with placebo, and moxifloxacin (400 mg PO)
Interventions
- OTHER Placebo IV
- DRUG Moxifloxacin 400mg
- DRUG ZTI-01
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2018-01-11 |
| Est. Completion | 2018-08-21 |
| Phase | Phase 1 |
What the finished NCT03709927 record still lists
NCT03709927 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo IV is the first listed.
NCT03709927 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03709927 about?
NCT03709927 is a clinical study titled "4-way Crossover QT Evaluation in Healthy Subjects". The purpose of this study is to evaluate if ZTI-01 (fosfomycin for injection), an investigational drug being developed to treat people with complicated urinary tract and kidney infections, has any effect on the electrical activity of the heart.
What is the current status of trial NCT03709927?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2018-01-11. Estimated completion is 2018-08-21.
What interventions are being tested in trial NCT03709927?
The interventions under investigation include: Placebo IV (OTHER), Moxifloxacin 400mg (DRUG), ZTI-01 (DRUG).
Who is sponsoring clinical trial NCT03709927?
This trial is sponsored by Nabriva Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03709927's enrollment target sits among peer trials
41 1125th of 2000 higher than 871 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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