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NCT03709888 · ClinicalTrials.gov registry record
Memantine XR and Pregabalin for Chemotherapy-Induced Peripheral Neuropathy
A clinical trial, sponsored by Saint John's Cancer Institute.
- Completed
- Registry status
- 20
- Enrollment target
NCT03709888: Completed study, sponsored by Saint John's Cancer Institute.
NCT03709888 is a clinical trial that has completed, run by Saint John's Cancer Institute. The registered enrollment target is 20 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03709888 has completed, sponsored by Saint John's Cancer Institute.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
Study Summary
Study is designed to assess the efficacy and safety of memantine XR and pregabalin in reducing neuropathic pain in patients with chemotherapy-induced peripheral neuropathy (CIPN) caused by prior treatment with any chemotherapy as measured by the Brief Pain Inventory- Short Form (BPI-SF). It will also determine the influence of these drugs on peripheral neuropathy-related functional status and quality of life (QOL) as measured by the EORTC QLQ-C30.
Primary Outcome
Absolute change in the average daily pain intensity as measured by the Brief Pain Inventory- Short Form (BPI-SF) from baseline to the end of 6 weeks measured by item # 5 of Brief Pain Inventory Score (BPI-SF). The BPI assesses pain at its "worst," "least," "average," and "now" (current pain). In clinical trials, the items "worst" and "average" have each been used singly to represent pain severity. A composite of the four pain items (a mean severity score) is sometimes presented as supplemental i
Interventions
- DRUG Memantine XR-pregabalin combination therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2016-07-09 |
| Est. Completion | 2021-04-29 |
What the finished NCT03709888 record still lists
NCT03709888 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Memantine XR-pregabalin combination therapy is the first listed.
NCT03709888 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03709888 about?
NCT03709888 is a clinical study titled "Memantine XR and Pregabalin for Chemotherapy-Induced Peripheral Neuropathy". Study is designed to assess the efficacy and safety of memantine XR and pregabalin in reducing neuropathic pain in patients with chemotherapy-induced peripheral neuropathy (CIPN) caused by prior treatment with any chemotherapy as measured by the Brief Pain Inventory- Short Form (BPI-SF). It will als...
What is the current status of trial NCT03709888?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2016-07-09. Estimated completion is 2021-04-29.
What interventions are being tested in trial NCT03709888?
The interventions under investigation include: Memantine XR-pregabalin combination therapy (DRUG).
Who is sponsoring clinical trial NCT03709888?
This trial is sponsored by Saint John's Cancer Institute, which has 19 total clinical trials registered on ClinicalTrials.gov.
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