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NCT03706053 · ClinicalTrials.gov registry record · Phase 3

Midodrine Use in Septic Shock

A Phase 3 study, sponsored by University of Virginia.

Terminated
Registry status
Phase 3
Development phase
10
Enrollment target

NCT03706053: Clinical Trial Phase 3 study, sponsored by University of Virginia.

NCT03706053 is a Phase 3 study that was terminated before completion, run by University of Virginia. The registered enrollment target is 10 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03706053, a Phase 3 study, was terminated before completion, sponsored by University of Virginia.

TERMINATED
Registry status
Phase 3
Development phase
10 participants
Enrollment target

Study Summary

The investigators aim to perform a randomized, double-blind, placebo-controlled trial to investigate the efficacy of midodrine in decreasing time to IV vasopressor liberation in patients with septic shock.

Primary Outcome

days without vasopressor adjusted with mortality

Interventions

  • OTHER placebo
  • DRUG Midodrine Hydrochloride

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2018-11-05
Est. Completion 2022-02-11
Phase Phase 3
University of Virginia

449 total trials

Why NCT03706053 stopped before completion

NCT03706053 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT03706053 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03706053 about?

NCT03706053 is a clinical study titled "Midodrine Use in Septic Shock". The investigators aim to perform a randomized, double-blind, placebo-controlled trial to investigate the efficacy of midodrine in decreasing time to IV vasopressor liberation in patients with septic shock.

What is the current status of trial NCT03706053?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 10 participants. The study started on 2018-11-05. Estimated completion is 2022-02-11.

What interventions are being tested in trial NCT03706053?

The interventions under investigation include: placebo (OTHER), Midodrine Hydrochloride (DRUG).

Who is sponsoring clinical trial NCT03706053?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03706053's enrollment target sits among peer trials

10 1989th of 2000 higher than 9 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03706053, the US trial registry maintained by the National Library of Medicine. NCT03706053 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.