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NCT03705962 · ClinicalTrials.gov registry record · Phase 3

Locally Applied Antibiotics for Infection Prophylaxis in Treatment of Open Fractures

A Phase 3 study, sponsored by University of Virginia.

Terminated
Registry status
Phase 3
Development phase
11
Enrollment target

NCT03705962 is a Phase 3 study that was terminated before completion, run by University of Virginia. The registered enrollment target is 11 participants.

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The verdict

NCT03705962, a Phase 3 study, was terminated before completion, sponsored by University of Virginia.

TERMINATED
Registry status
Phase 3
Development phase
11 participants
Enrollment target

Study Summary

The primary objective of this study is to investigate the effectiveness of local antibiotic versus placebo in the prevention of infections in open fractures. The study will assess whether local treatment of open fractures with the antibiotic tobramycin (in addition to standard systemic antibiotics) will decrease the risk and rate of infection, and rate of re-operation. This will be studied using a randomized controlled clinical trial design in adult population of age 18-70 years who present with open fractures. About 133 subjects will be recruited in this study at UVA.

Interventions

  • DRUG Tobramycin
  • OTHER Placebo: normal saline

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2015-07
Est. Completion 2019-03-07
Phase Phase 3

Sponsor

University of Virginia

449 total trials

What the Registry Record Tells You About NCT03705962

The ClinicalTrials.gov registry entry for NCT03705962 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Tobramycin is the first listed.

NCT03705962 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03705962 about?

NCT03705962 is a clinical study titled "Locally Applied Antibiotics for Infection Prophylaxis in Treatment of Open Fractures". The primary objective of this study is to investigate the effectiveness of local antibiotic versus placebo in the prevention of infections in open fractures. The study will assess whether local treatment of open fractures with the antibiotic tobramycin (in addition to standard systemic antibiotics) ...

What is the current status of trial NCT03705962?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 11 participants. The study started on 2015-07. Estimated completion is 2019-03-07.

What interventions are being tested in trial NCT03705962?

The interventions under investigation include: Tobramycin (DRUG), Placebo: normal saline (OTHER).

Who is sponsoring clinical trial NCT03705962?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.