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NCT03705715 · ClinicalTrials.gov registry record · Phase 1
Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: a Dimensional Approach
A Phase 1 study of Neuropsychiatric Syndromes, sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT03705715: Recruiting Phase 1 study of Neuropsychiatric Syndromes, sponsored by The University of Texas Health Science Center, Houston.
NCT03705715 is a Phase 1 study of Neuropsychiatric Syndromes that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 200 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (233% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03705715, a Phase 1 study of Neuropsychiatric Syndromes, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research is to determine whether there is more extensive inflammation in the brain of people with clinical evidence of neuropsychiatric syndromes, such as mood disorder, chronic pain syndrome, dementia, traumatic brain injury, or substance abuse. The research will also explore whether there is more inflammation in patients with more neuropsychiatric symptoms. Inflammation in the brain will identified by using Positron Emission Tomography (PET) with the radiotracer \[11C\]PBR-28 or \[11C\]ER176.
Conditions Studied
Interventions
- DRUG PET with radiotracer [11C]PBR-28 ( or [11C]ER176)
- OTHER Affective challenge
Study Locations (1)
Texas
- BBSB at UTHealth - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2017-05-01 |
| Est. Completion | 2028-08 |
| Phase | Phase 1 |
What NCT03705715 shows while recruiting
NCT03705715 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (233% higher).
The record links to 1 condition, with Neuropsychiatric Syndromes appearing as the primary indexed condition, and to 2 interventions - of which PET with radiotracer [11C]PBR-28 ( or [11C]ER176) is the first listed.
NCT03705715 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT03705715 about?
NCT03705715 is a clinical study titled "Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: a Dimensional Approach". The purpose of this research is to determine whether there is more extensive inflammation in the brain of people with clinical evidence of neuropsychiatric syndromes, such as mood disorder, chronic pain syndrome, dementia, traumatic brain injury, or substance abuse. The research will also explore wh...
What is the current status of trial NCT03705715?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 200 participants. The study started on 2017-05-01. Estimated completion is 2028-08.
What conditions does trial NCT03705715 study?
This clinical trial studies the following conditions: Neuropsychiatric Syndromes.
What interventions are being tested in trial NCT03705715?
The interventions under investigation include: PET with radiotracer [11C]PBR-28 ( or [11C]ER176) (DRUG), Affective challenge (OTHER).
Who is sponsoring clinical trial NCT03705715?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03705715 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03705715's enrollment target sits among peer trials
200 259th of 2000 higher than 1,724 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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