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NCT03704376 · ClinicalTrials.gov registry record · Phase 4

Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction

A Phase 4 study of Anterior Cruciate Ligament Injury, sponsored by The University of Texas Health Science Center, Houston.

Completed
Registry status
Phase 4
Development phase
125
Enrollment target
1
Study location

NCT03704376: Completed Phase 4 study of Anterior Cruciate Ligament Injury, sponsored by The University of Texas Health Science Center, Houston.

NCT03704376 is a Phase 4 study of Anterior Cruciate Ligament Injury that has completed, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 125 participants, below the 218-participant average among 8 other Anterior Cruciate Ligament Injury trials with a reported enrollment target (43% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03704376, a Phase 4 study of Anterior Cruciate Ligament Injury, has completed, sponsored by The University of Texas Health Science Center, Houston.

COMPLETED
Registry status
Phase 4
Development phase
125 participants
Enrollment target
1
Study location

Study Summary

This study will examine the potential differences between femoral nerve blockade (FNB) and adductor canal blockade (ACB) for pain control and quadriceps muscle activation for patients following anterior cruciate ligament (ACL) reconstruction.

Primary Outcome

Quadriceps muscle activation was examined using surface electromyography (sEMG) of the vastus medialis oblique muscle. Peak sEMG activity was recorded in microvolts (uV) on the surgical and contralateral limbs while performing five maximal effort isometric contractions in full knee extension--the reported values are equal to the quadriceps sEMG in uV of the contralateral limb minus the quadriceps sEMG in uV of the surgical limb.

Interventions

  • DRUG 30 ml of 0.2% ropivacaine
  • DRUG 15 ml of 0.2% ropivacaine
  • DRUG 100 mcg clonidine
  • DEVICE High-frequency linear ultrasound transducer

Study Locations (1)

Texas

  • The University of Texas Health Science Center-Houston - Houston

Trial Details

FieldValue
Enrollment Target 125 participants
Start Date 2016-02-01
Est. Completion 2017-11-16
Phase Phase 4

What the finished NCT03704376 record still lists

NCT03704376 is an interventional study that assigns participants to a tested intervention. The registered 125 participants enrollment target is mid-sized for trials with a published cap, below the 218-participant average among 8 other Anterior Cruciate Ligament Injury trials with a reported enrollment target (43% lower).

The record links to 1 condition, with Anterior Cruciate Ligament Injury appearing as the primary indexed condition, and to 4 interventions - of which 30 ml of 0.2% ropivacaine is the first listed.

NCT03704376 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT03704376 about?

NCT03704376 is a clinical study titled "Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction". This study will examine the potential differences between femoral nerve blockade (FNB) and adductor canal blockade (ACB) for pain control and quadriceps muscle activation for patients following anterior cruciate ligament (ACL) reconstruction.

What is the current status of trial NCT03704376?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 125 participants. The study started on 2016-02-01. Estimated completion is 2017-11-16.

What conditions does trial NCT03704376 study?

This clinical trial studies the following conditions: Anterior Cruciate Ligament Injury.

What interventions are being tested in trial NCT03704376?

The interventions under investigation include: 30 ml of 0.2% ropivacaine (DRUG), 15 ml of 0.2% ropivacaine (DRUG), 100 mcg clonidine (DRUG), High-frequency linear ultrasound transducer (DEVICE).

Who is sponsoring clinical trial NCT03704376?

This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03704376 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Anterior Cruciate Ligament Injury

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03704376's enrollment target sits among peer trials

125 3rd of 8 higher than 6 of 8 other Anterior Cruciate Ligament Injury trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Anterior Cruciate Ligament Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03704376, the US trial registry maintained by the National Library of Medicine. NCT03704376 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.