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NCT03699644 · ClinicalTrials.gov registry record
Multimodal Ocular Imaging in Neurodegeneration
A clinical trial, sponsored by University of Michigan.
- Completed
- Registry status
- 16
- Enrollment target
NCT03699644 is a clinical trial that has completed, run by University of Michigan. The registered enrollment target is 16 participants.
The verdict
NCT03699644 has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- 16 participants
- Enrollment target
Study Summary
Alzheimer's disease (AD) and frontotemporal dementia (FTD) are two of the most common types of age-related neurodegenerative disorders. Identifying at-risk patients and gauging disease progression in a non-invasive manner would be invaluable. Early and correct diagnosis is crucial for coordinating supportive care, patient expectations, caregiver arrangements and family planning. In addition, as treatments become available, beginning therapy early in the disease before symptoms become severe will be important. Multimodal ocular imaging (MOI) includes an ophthalmic (eye) exam and eye photographs to evaluate different layers of the retina, which is the light sensing layer of the eye. Newer technologies make it possible to visualize the disease process occurring in AD and FTD by using MOI to look at the retina, since the retina is fundamentally an outward extension of the brain itself. This study will attempt to correlate signs of disease in the retina, as determined by MOI, with plaque buildup in the brain as seen by imaging. This will demonstrate the sensitivity and specificity of MOI for diagnosing AD and FTD in a noninvasive manner.
Interventions
- DEVICE Magnetic Resonance Imaging (MRI)
- DEVICE Spectral-Domain Optical Coherence Tomography (SD-OCT)
- DEVICE Positron Emission Tomography (PET)
- DIAGNOSTIC_TEST Comprehensive Ophthalmic Examination
- DEVICE Fundus Photography
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2019-01-04 |
| Est. Completion | 2019-04-03 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03699644
The ClinicalTrials.gov registry entry for NCT03699644 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which Magnetic Resonance Imaging (MRI) is the first listed.
NCT03699644 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03699644 about?
NCT03699644 is a clinical study titled "Multimodal Ocular Imaging in Neurodegeneration". Alzheimer's disease (AD) and frontotemporal dementia (FTD) are two of the most common types of age-related neurodegenerative disorders. Identifying at-risk patients and gauging disease progression in a non-invasive manner would be invaluable. Early and correct diagnosis is crucial for coordinating s...
What is the current status of trial NCT03699644?
This trial is currently completed. The enrollment target is 16 participants. The study started on 2019-01-04. Estimated completion is 2019-04-03.
What interventions are being tested in trial NCT03699644?
The interventions under investigation include: Magnetic Resonance Imaging (MRI) (DEVICE), Spectral-Domain Optical Coherence Tomography (SD-OCT) (DEVICE), Positron Emission Tomography (PET) (DEVICE), Comprehensive Ophthalmic Examination (DIAGNOSTIC_TEST), Fundus Photography (DEVICE).
Who is sponsoring clinical trial NCT03699644?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
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