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NCT03698162 · ClinicalTrials.gov registry record · NA
Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases
A NA study, sponsored by University of Southern California.
- Terminated
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT03698162: Clinical Trial NA study, sponsored by University of Southern California.
NCT03698162 is a NA study that was terminated before completion, run by University of Southern California. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03698162, a NA study, was terminated before completion, sponsored by University of Southern California.
- TERMINATED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) is a potentially powerful diagnostic tool for the management of brain cancer and other conditions in which the blood-brain barrier is compromised. This trial studies how well precise DCE MRI works in diagnosing participants with high grade glioma that has come back or melanoma that has spread to the brain. The specially-tailored acquisition and reconstruction (STAR) DCE MRI could provide improved assessment of brain tumor status and response to therapy.
Primary Outcome
The raw data will be acquired at the voxel level. Then the analytic parameters will be extracted from voxel-wise data such as the mean, median, interquartile range, skewness and kurtosis. Receiver-operating characteristic curves (ROC) will be used to illustrate the univariate prediction accuracy for each parameter in predicting the clinically determined outcome. The pattern of change with different clinical response status will be visually illustrated using spaghetti plots or other graphical app
Interventions
- OTHER Dynamic Contrast-Enhanced Magnetic Resonance Imaging
- OTHER Bevacizumab Injection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2021-04-13 |
| Est. Completion | 2025-03-01 |
| Phase | NA |
Why NCT03698162 stopped before completion
NCT03698162 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Dynamic Contrast-Enhanced Magnetic Resonance Imaging is the first listed.
NCT03698162 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03698162 about?
NCT03698162 is a clinical study titled "Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases". Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) is a potentially powerful diagnostic tool for the management of brain cancer and other conditions in which the blood-brain barrier is compromised. This trial studies how well precise DCE MRI works in diagnosing participants with high g...
What is the current status of trial NCT03698162?
This trial is currently terminated. It is a NA study. The enrollment target is 15 participants. The study started on 2021-04-13. Estimated completion is 2025-03-01.
What interventions are being tested in trial NCT03698162?
The interventions under investigation include: Dynamic Contrast-Enhanced Magnetic Resonance Imaging (OTHER), Bevacizumab Injection (OTHER).
Who is sponsoring clinical trial NCT03698162?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03698162's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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