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NCT03690427 · ClinicalTrials.gov registry record · NA

The Cardiovascular Effects of Electronic Hookah Vaping

A NA study, sponsored by University of California, Los Angeles.

Completed
Registry status
NA
Development phase
19
Enrollment target

NCT03690427: Completed NA study, sponsored by University of California, Los Angeles.

NCT03690427 is a NA study that has completed, run by University of California, Los Angeles. The registered enrollment target is 19 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03690427, a NA study, has completed, sponsored by University of California, Los Angeles.

COMPLETED
Registry status
NA
Development phase
19 participants
Enrollment target

Study Summary

Hookah (water-pipe) tobacco smoking has quickly grown to become a major global tobacco epidemic among youth; with electronic (e-) hookahs more recently increasing in popularity especially among young female adults, who endorse marketing claims that these products are a safer alternative to traditional hookah, but scientific evidence is lacking. The study aims to elucidate the comparative effects of traditional hookah smoking vs. e-hookah vaping on human vascular and endothelial function; and examine the role of inflammation and oxidative stress, as likely mechanisms in hookah-related cardiovascular disease pathogenesis.

Primary Outcome

Using ultrasound, FMD of the brachial artery induced by reactive hyperemia, was used to measure endothelium-dependent vasodilator function. Baseline diameter and velocity were recorded for 45 seconds and resumed 30 seconds before cuff deflation and continuously for 2 minutes after deflation to obtain true peak vasodilatory response.

Interventions

  • OTHER Traditional hookah smoking
  • OTHER Electronic hookah vaping

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2018-12-11
Est. Completion 2021-09-27
Phase NA

What the finished NCT03690427 record still lists

NCT03690427 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Traditional hookah smoking is the first listed.

NCT03690427 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03690427 about?

NCT03690427 is a clinical study titled "The Cardiovascular Effects of Electronic Hookah Vaping". Hookah (water-pipe) tobacco smoking has quickly grown to become a major global tobacco epidemic among youth; with electronic (e-) hookahs more recently increasing in popularity especially among young female adults, who endorse marketing claims that these products are a safer alternative to tradition...

What is the current status of trial NCT03690427?

This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2018-12-11. Estimated completion is 2021-09-27.

What interventions are being tested in trial NCT03690427?

The interventions under investigation include: Traditional hookah smoking (OTHER), Electronic hookah vaping (OTHER).

Who is sponsoring clinical trial NCT03690427?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03690427's enrollment target sits among peer trials

19 1861st of 2000 higher than 138 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03690427, the US trial registry maintained by the National Library of Medicine. NCT03690427 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.