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NCT03684642 · ClinicalTrials.gov registry record · Phase 3

Efficacy and Safety of Efpeglenatide Versus Dulaglutide in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin

A Phase 3 study, sponsored by Sanofi.

Terminated
Registry status
Phase 3
Development phase
908
Enrollment target

NCT03684642 is a Phase 3 study that was terminated before completion, run by Sanofi. The registered enrollment target is 908 participants.

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The verdict

NCT03684642, a Phase 3 study, was terminated before completion, sponsored by Sanofi.

TERMINATED
Registry status
Phase 3
Development phase
908 participants
Enrollment target

Study Summary

Primary Objective: To demonstrate the non-inferiority of once weekly injection of efpeglenatide in comparison to once weekly injection of dulaglutide on glycated hemoglobin (HbA1c) change in participants with Type 2 diabetes mellitus (T2DM) inadequately controlled with metformin. Secondary Objectives: * To demonstrate the superiority of once weekly injection of efpeglenatide with once weekly injection of dulaglutide on glycemic control. * To demonstrate the superiority of once weekly injection of efpeglenatide with once weekly injection of dulaglutide on body weight. * To evaluate the safety of once weekly injection of efpeglenatide and once weekly injection of dulaglutide.

Interventions

  • DRUG Dulaglutide
  • DRUG Efpeglenatide
  • DRUG Background therapy Metformin

Trial Details

FieldValue
Enrollment Target 908 participants
Start Date 2018-09-26
Est. Completion 2020-11-17
Phase Phase 3

Sponsor

Sanofi

713 total trials

What the Registry Record Tells You About NCT03684642

The ClinicalTrials.gov registry entry for NCT03684642 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 908 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sanofi, which has 713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Dulaglutide is the first listed.

NCT03684642 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03684642 about?

NCT03684642 is a clinical study titled "Efficacy and Safety of Efpeglenatide Versus Dulaglutide in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin". Primary Objective: To demonstrate the non-inferiority of once weekly injection of efpeglenatide in comparison to once weekly injection of dulaglutide on glycated hemoglobin (HbA1c) change in participants with Type 2 diabetes mellitus (T2DM) inadequately controlled with metformin. Secondary Objecti...

What is the current status of trial NCT03684642?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 908 participants. The study started on 2018-09-26. Estimated completion is 2020-11-17.

What interventions are being tested in trial NCT03684642?

The interventions under investigation include: Dulaglutide (DRUG), Efpeglenatide (DRUG), Background therapy Metformin (DRUG).

Who is sponsoring clinical trial NCT03684642?

This trial is sponsored by Sanofi, which has 713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.