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NCT03682757 · ClinicalTrials.gov registry record

Post-Injury Platelet Biology: Mechanisms and Outcomes

A clinical trial, sponsored by University of California, San Francisco.

Completed
Registry status
367
Enrollment target

NCT03682757 is a clinical trial that has completed, run by University of California, San Francisco. The registered enrollment target is 367 participants.

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The verdict

NCT03682757 has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
367 participants
Enrollment target

Study Summary

Trauma-induced coagulopathy is a central cause of preventable deaths from hemorrhage after injury. The contribution and impact of altered post injury platelet biology on trauma-induced coagulopathy is not well understood despite the pivotal contribution of platelets to normal coagulation and endothelial integrity. The central hypothesis for this study is that severe injury and shock drive altered platelet activation, platelet aggregation, and platelet-endothelial interactions that are associated with increased rates of transfusion, organ failure, and mortality. This study will investigate these causal pathways, mechanisms, and associated outcomes in a prospective observational trauma cohort through collection of biospecimens and detailed clinical data.

Trial Details

FieldValue
Enrollment Target 367 participants
Start Date 2018-09-20
Est. Completion 2023-09-30

What the Registry Record Tells You About NCT03682757

The ClinicalTrials.gov registry entry for NCT03682757 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 367 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT03682757 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03682757 about?

NCT03682757 is a clinical study titled "Post-Injury Platelet Biology: Mechanisms and Outcomes". Trauma-induced coagulopathy is a central cause of preventable deaths from hemorrhage after injury. The contribution and impact of altered post injury platelet biology on trauma-induced coagulopathy is not well understood despite the pivotal contribution of platelets to normal coagulation and endothe...

What is the current status of trial NCT03682757?

This trial is currently completed. The enrollment target is 367 participants. The study started on 2018-09-20. Estimated completion is 2023-09-30.

Who is sponsoring clinical trial NCT03682757?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.