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NCT03680144 · ClinicalTrials.gov registry record · NA
Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases
A NA study, sponsored by Emory University.
- Completed
- Registry status
- NA
- Development phase
- 8
- Enrollment target
NCT03680144: Completed NA study, sponsored by Emory University.
NCT03680144 is a NA study that has completed, run by Emory University. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03680144, a NA study, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
Study Summary
This trial studies how well dynamic susceptibility contrast-magnetic resonance imaging (MRI) works in determining radiation necrosis and tumor progression in participants with cancer that has spread to the brain and are being treated with radiation therapy. Diagnostic procedures, such as dynamic susceptibility contrast-MRI, may improve the ability to determine indeterminate post-treatment changes seen on imaging after radiation therapy.
Primary Outcome
Image processing will occur in a blinded manner using nordicICE software (NordicNeuroLab AS, Bergen, Norway). Signal-intensity curves will be created per voxel. Regions of interest will be designated around the contrast enhancing lesion as seen on T1-post contrast MR. An additional contralateral area of normal-appearing white matter will be designated in the same axial plane to standardize the data. rCBV is calculated as the ratio of the CBV within the enhancing region to the CBV within the cont
Interventions
- PROCEDURE Magnetic Resonance Imaging (MRI)
- PROCEDURE Dynamic Susceptibility Contrast-MRI (DSC-MRI)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2018-11-28 |
| Est. Completion | 2021-06-15 |
| Phase | NA |
What the finished NCT03680144 record still lists
NCT03680144 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Magnetic Resonance Imaging (MRI) is the first listed.
NCT03680144 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03680144 about?
NCT03680144 is a clinical study titled "Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases". This trial studies how well dynamic susceptibility contrast-magnetic resonance imaging (MRI) works in determining radiation necrosis and tumor progression in participants with cancer that has spread to the brain and are being treated with radiation therapy. Diagnostic procedures, such as dynamic sus...
What is the current status of trial NCT03680144?
This trial is currently completed. It is a NA study. The enrollment target is 8 participants. The study started on 2018-11-28. Estimated completion is 2021-06-15.
What interventions are being tested in trial NCT03680144?
The interventions under investigation include: Magnetic Resonance Imaging (MRI) (PROCEDURE), Dynamic Susceptibility Contrast-MRI (DSC-MRI) (PROCEDURE).
Who is sponsoring clinical trial NCT03680144?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03680144's enrollment target sits among peer trials
8 1976th of 2000 higher than 19 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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