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NCT03677778 · ClinicalTrials.gov registry record · NA
Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade
A NA study, sponsored by Stanford University.
- Completed
- Registry status
- NA
- Development phase
- 43
- Enrollment target
NCT03677778: Completed NA study, sponsored by Stanford University.
NCT03677778 is a NA study that has completed, run by Stanford University. The registered enrollment target is 43 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03677778, a NA study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- NA
- Development phase
- 43 participants
- Enrollment target
Study Summary
One of the most frequently performed peripheral nerve blocks (the injection of local anesthetic near nerves to block sensation/ movement to a specific part of the body) is the interscalene brachial plexus block for upper extremity surgeries. This type of block can unmask underlying respiratory issues such as shortness of breath due to a well-known and typically insignificant side effect of temporary diaphragmatic paralysis. The nerve block may be able to use saline solution to wash out the local anesthetic and potentially reverse this respiratory side effect. Specifically, the goal of this study is to determine if the injection of saline through the nerve block catheter reverses blockade of the phrenic nerve supplying the diaphragm, without affecting the ability of the nerve block to provide pain control after surgery.
Primary Outcome
Spirometry data will be collected using a digital spirometer before nerve block is placed, after surgery, and after receiving either the placebo or treatment.
Interventions
- OTHER Placebo
- PROCEDURE Normal saline injected via interscalene nerve catheter
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2018-10-22 |
| Est. Completion | 2022-07-07 |
| Phase | NA |
What the finished NCT03677778 record still lists
NCT03677778 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03677778 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03677778 about?
NCT03677778 is a clinical study titled "Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade". One of the most frequently performed peripheral nerve blocks (the injection of local anesthetic near nerves to block sensation/ movement to a specific part of the body) is the interscalene brachial plexus block for upper extremity surgeries. This type of block can unmask underlying respiratory issue...
What is the current status of trial NCT03677778?
This trial is currently completed. It is a NA study. The enrollment target is 43 participants. The study started on 2018-10-22. Estimated completion is 2022-07-07.
What interventions are being tested in trial NCT03677778?
The interventions under investigation include: Placebo (OTHER), Normal saline injected via interscalene nerve catheter (PROCEDURE).
Who is sponsoring clinical trial NCT03677778?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03677778's enrollment target sits among peer trials
43 1435th of 2000 higher than 565 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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