Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03674697 · ClinicalTrials.gov registry record · NA
The Effect of Light Therapy on Post-Surgical Pain
A NA study of Acute Pain and Arthropathy of Knee, sponsored by University of Arizona.
- Active
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT03674697: Active NA study of Acute Pain and Arthropathy of Knee, sponsored by University of Arizona.
NCT03674697 is a NA study of Acute Pain and Arthropathy of Knee that is active but no longer recruiting, run by University of Arizona. The registered enrollment target is 70 participants, below the 267-participant average among 50 other Acute Pain trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03674697, a NA study of Acute Pain and Arthropathy of Knee, is active but no longer recruiting, sponsored by University of Arizona.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective randomized clinical trial study to investigate two main aspects. The first aspect is to investigate the efficacy exposure to green light emitting diode (GLED) in reducing postoperative opioid medications requirements by 20% as the primary outcome amongst patients scheduled for elective total knee replacement surgery (knee arthroplasty). The second aspect is to reduce postoperative pain by 30%, improve preoperative anxiety by 30%, and improve the quality of sleep pre and postoperatively by 30%. Seventy participants scheduled for elective unilateral primary total knee arthroplasty (total knee replacement) will be recruited from the pain clinic or from the orthopedic surgery clinics at Banner-University Medical Center by the pain or orthopedic physicians who are key personnel of this study. Once a participant is identified, he/she will meet with one of the research team members to explain the nature of the clinical trial and undergo a standard of care medical history gathering and baseline physical examinations. If the participant meets all the inclusion and have no exclusion criteria, he/she will be presented with a written consent in English to explain all the risk and benefits of this clinical trial. Once a participant signs a consent, he or she will be randomized by the study statistician, in a 1:1 ratio to either a GLED group (treatment) or white light-emitting diode (WLED) group (control). The participant will be trained on how to use the light device by one of the research team members. All participants will be exposed to either GLED or WLED for 8 weeks prior to surgery and two additional weeks after surgery.
Primary Outcome
Change in postoperative opioid medications requirements by 20% as assessed by opioid medication logs
Conditions Studied
Interventions
- DEVICE Green LED light therapy
- DEVICE White LED light therapy
Study Locations (1)
Arizona
- Banner University Medical Center Tucson - Tucson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2018-09-05 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
What the registry record for NCT03674697 still lists
NCT03674697 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 267-participant average among 50 other Acute Pain trials with a reported enrollment target (74% lower).
The record links to 2 conditions, with Acute Pain appearing as the primary indexed condition, and to 2 interventions - of which Green LED light therapy is the first listed.
NCT03674697 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT03674697 about?
NCT03674697 is a clinical study titled "The Effect of Light Therapy on Post-Surgical Pain". This is a prospective randomized clinical trial study to investigate two main aspects. The first aspect is to investigate the efficacy exposure to green light emitting diode (GLED) in reducing postoperative opioid medications requirements by 20% as the primary outcome amongst patients scheduled for ...
What is the current status of trial NCT03674697?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2018-09-05. Estimated completion is 2027-12-31.
What conditions does trial NCT03674697 study?
This clinical trial studies the following conditions: Acute Pain, Arthropathy of Knee.
What interventions are being tested in trial NCT03674697?
The interventions under investigation include: Green LED light therapy (DEVICE), White LED light therapy (DEVICE).
Who is sponsoring clinical trial NCT03674697?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03674697 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03674697's enrollment target sits among peer trials
70 33rd of 50 higher than 17 of 50 other Acute Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans
RECRUITING · NA
-
Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises
RECRUITING · NA
-
Does Patient Testimonial Improve the Pain Relief Derived From a Brief Intervention
RECRUITING · NA
-
Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure
RECRUITING · NA
-
The Implementation of a Post-operative Communication App to Improve Pain Control and Opioid Use
RECRUITING · NA
-
Pharmacogenetic-guided Choice of Post-surgery Analgesics
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00969111 · 70 participants · NA
Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy
- NCT01712620 · 70 participants · Phase 2
Spironolactone for Pulmonary Arterial Hypertension
- NCT02143830 · 70 participants · Phase 2
HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy
- NCT02601339 · 70 participants
NIRS Monitoring in Premature Infants
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI