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Ribociclib and Letrozole Treatment in Ovarian Cancer
NCT03673124 · View on ClinicalTrials.gov ↗
Study Summary
The study evaluates the response to treatment with Ribociclib and Letrozole in patients with low grade serous cancer of the ovary, fallopian tube or peritoneum.
Conditions Studied
Interventions
- DRUG Letrozole
- DRUG Ribociclib
Study Locations (20)
Florida
- UF Heath — Gainesville
- Moffitt Cancer Center — Tampa
New Jersey
- Hackensack University Medical Center — Hackensack
- The Valley Hospital Inc. — Ridgewood
New Mexico
- New Mexico Cancer Care Alliance/University of New Mexico Comprehensive Cancer Center — Albuquerque
- Southwest Gynecologic Oncology Associates — Albuquerque
Ohio
- Miami Valley Hospital — Centerville
- The Ohio State Comprehensive Cancer Center — Columbus
Oklahoma
- University of Oklahoma Health Sciences Center — Oklahoma City
- Oklahoma Cancer Care Specialists and Research Institute , LLC — Tulsa
Pennsylvania
- Western Pennsylvania Hospital/West Penn Hospital — Pittsburgh
- Abington Memorial Hospital — Willow Grove
California
- University of California, San Francisco — San Francisco
Georgia
- Northside Hospital — Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 51 participants |
| Start Date | 2019-05-20 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03673124
The ClinicalTrials.gov registry entry for NCT03673124 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 51 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gynecologic Oncology Group, which has 61 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Low Grade Serous Carcinoma appearing as the primary indexed condition, and to 2 interventions — of which Letrozole is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03673124 reports 20 study locations spanning 14 distinct geographic areas — top geographies include Florida, New Jersey, New Mexico. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03673124 about?
NCT03673124 is a clinical study titled "Ribociclib and Letrozole Treatment in Ovarian Cancer". The study evaluates the response to treatment with Ribociclib and Letrozole in patients with low grade serous cancer of the ovary, fallopian tube or peritoneum.
What is the current status of trial NCT03673124?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 51 participants. The study started on 2019-05-20. Estimated completion is 2026-12-31.
What conditions does trial NCT03673124 study?
This clinical trial studies the following conditions: Low Grade Serous Carcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03673124?
The interventions under investigation include: Letrozole (DRUG), Ribociclib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03673124?
This trial is sponsored by Gynecologic Oncology Group, which has 61 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03673124 being conducted?
This trial has 20 study locations across California, Florida, Georgia, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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