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NCT03670355 · ClinicalTrials.gov registry record · Phase 1
Pharmacokinetic and Safety Study of a 90 Day Intravaginal Ring Containing Tenofovir
A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Completed
- Registry status
- Phase 1
- Development phase
- 49
- Enrollment target
NCT03670355: Completed Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT03670355 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 49 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (18% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03670355, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 49 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the pharmacokinetics (PK) and safety of a 90-day intravaginal ring (IVR) containing tenofovir (TFV).
Primary Outcome
TFV concentrations as assessed by drug detection testing in plasma samples collected at multiple timepoints during the study.
Interventions
- DRUG Tenofovir (TFV) IVR
- DRUG Placebo IVR
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 49 participants |
| Start Date | 2019-01-02 |
| Est. Completion | 2019-09-25 |
| Phase | Phase 1 |
What the finished NCT03670355 record still lists
NCT03670355 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (18% lower).
The record links to 0 conditions, and to 2 interventions - of which Tenofovir (TFV) IVR is the first listed.
NCT03670355 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03670355 about?
NCT03670355 is a clinical study titled "Pharmacokinetic and Safety Study of a 90 Day Intravaginal Ring Containing Tenofovir". The purpose of this study is to evaluate the pharmacokinetics (PK) and safety of a 90-day intravaginal ring (IVR) containing tenofovir (TFV).
What is the current status of trial NCT03670355?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 49 participants. The study started on 2019-01-02. Estimated completion is 2019-09-25.
What interventions are being tested in trial NCT03670355?
The interventions under investigation include: Tenofovir (TFV) IVR (DRUG), Placebo IVR (DRUG).
Who is sponsoring clinical trial NCT03670355?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03670355's enrollment target sits among peer trials
49 1017th of 2000 higher than 976 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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