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NCT03665454 · ClinicalTrials.gov registry record · Phase 1
PF 06412562 in Subjects With Advanced Stage Parkinson's Disease
A Phase 1 study, sponsored by Milton S. Hershey Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
NCT03665454: Completed Phase 1 study, sponsored by Milton S. Hershey Medical Center.
NCT03665454 is a Phase 1 study that has completed, run by Milton S. Hershey Medical Center. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03665454, a Phase 1 study, has completed, sponsored by Milton S. Hershey Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
The purpose of this study is to test the safety and tolerability of the investigational drug PF-06412562 compared to the current medical standard of care medication for Parkinson's disease, carbidopa/levodopa. This research also is being done to find out if the investigational drug PF-06412562 can help improve the motor (movement) function, alertness, and cognitive (thinking) skills of people who are considered to be in the advanced-stage of Parkinson's disease. In this study, PF06412562 is 'investigational,' which means that it is experimental and has not been approved by the US Food and Drug Administration (FDA), but can be used in clinical research studies such as this one.
Primary Outcome
NA (mmol/L), K(mmol/L), HCO3(mmol/L)
Interventions
- DRUG PF-06412562
- DRUG Standard of Care Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2018-09-24 |
| Est. Completion | 2019-04-21 |
| Phase | Phase 1 |
What the finished NCT03665454 record still lists
NCT03665454 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 2 interventions - of which PF-06412562 is the first listed.
NCT03665454 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03665454 about?
NCT03665454 is a clinical study titled "PF 06412562 in Subjects With Advanced Stage Parkinson's Disease". The purpose of this study is to test the safety and tolerability of the investigational drug PF-06412562 compared to the current medical standard of care medication for Parkinson's disease, carbidopa/levodopa. This research also is being done to find out if the investigational drug PF-06412562 can h...
What is the current status of trial NCT03665454?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2018-09-24. Estimated completion is 2019-04-21.
What interventions are being tested in trial NCT03665454?
The interventions under investigation include: PF-06412562 (DRUG), Standard of Care Placebo (DRUG).
Who is sponsoring clinical trial NCT03665454?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03665454's enrollment target sits among peer trials
8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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