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NCT03658135 · ClinicalTrials.gov registry record · Phase 1
BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TES
A Phase 1 study, sponsored by University of California, San Francisco.
- Terminated
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
NCT03658135: Clinical Trial Phase 1 study, sponsored by University of California, San Francisco.
NCT03658135 is a Phase 1 study that was terminated before completion, run by University of California, San Francisco. The registered enrollment target is 22 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03658135, a Phase 1 study, was terminated before completion, sponsored by University of California, San Francisco.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
Study Summary
A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Parallel Cohort Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of Intravenously Infused BIIB092 in Patients with Four Different Primary Tauopathy Syndromes
Primary Outcome
Assess adverse events during 20 weeks administration BIIB092 or Placebo
Interventions
- OTHER Placebo
- DRUG BIIB092
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2018-09-12 |
| Est. Completion | 2019-12-13 |
| Phase | Phase 1 |
Why NCT03658135 stopped before completion
NCT03658135 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03658135 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03658135 about?
NCT03658135 is a clinical study titled "BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TES". A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Parallel Cohort Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of Intravenously Infused BIIB092 in Patients with Four Different Primary Tauopathy Syndromes
What is the current status of trial NCT03658135?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2018-09-12. Estimated completion is 2019-12-13.
What interventions are being tested in trial NCT03658135?
The interventions under investigation include: Placebo (OTHER), BIIB092 (DRUG).
Who is sponsoring clinical trial NCT03658135?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03658135's enrollment target sits among peer trials
22 1601st of 2000 higher than 386 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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