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NCT03652818 · ClinicalTrials.gov registry record · Phase 2
Dental Pain Study of Analgesics in Patients Undergoing Molar Removal
A Phase 2 study, sponsored by Nevakar.
- Completed
- Registry status
- Phase 2
- Development phase
- 115
- Enrollment target
NCT03652818: Completed Phase 2 study, sponsored by Nevakar.
NCT03652818 is a Phase 2 study that has completed, run by Nevakar. The registered enrollment target is 115 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (14% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03652818, a Phase 2 study, has completed, sponsored by Nevakar.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 115 participants
- Enrollment target
Study Summary
* Accessing the efficacy and safety of pregabalin when used alone and in combo with acetaminophen in a dental pain model. * To test whether pre-operative dose of pregabalin increases the time to significant post-operative pain (NRS ≥ 5), and hence time to first analgesia consumed post-operatively.
Primary Outcome
Beginning post-surgery (at initiation of Dose 2), Pain Intensity was self-reported over 24 hours, using a pain rating of 0-10 on the Numerical Rating Scale (NRS), with score between 0-10 (0= no pain; 10 = pain as bad as can be). Time weighted sum pain intensity difference scores are reported over 0 to 24 hours. Last observation carried forward method was used.
Interventions
- DRUG Pre-Op pregabalin
- DRUG Pre-Op Placebo 1
- DRUG Post-Op pregabalin
- DRUG Post-Op Placebo 1
- DRUG Post-Op Placebo 2
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 115 participants |
| Start Date | 2018-06-15 |
| Est. Completion | 2018-09-20 |
| Phase | Phase 2 |
What the finished NCT03652818 record still lists
NCT03652818 is an interventional study that assigns participants to a tested intervention. The registered 115 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (14% lower).
The record links to 0 conditions, and to 5 interventions - of which Pre-Op pregabalin is the first listed.
NCT03652818 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03652818 about?
NCT03652818 is a clinical study titled "Dental Pain Study of Analgesics in Patients Undergoing Molar Removal". * Accessing the efficacy and safety of pregabalin when used alone and in combo with acetaminophen in a dental pain model. * To test whether pre-operative dose of pregabalin increases the time to significant post-operative pain (NRS ≥ 5), and hence time to first analgesia consumed post-operatively.
What is the current status of trial NCT03652818?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 115 participants. The study started on 2018-06-15. Estimated completion is 2018-09-20.
What interventions are being tested in trial NCT03652818?
The interventions under investigation include: Pre-Op pregabalin (DRUG), Pre-Op Placebo 1 (DRUG), Post-Op pregabalin (DRUG), Post-Op Placebo 1 (DRUG), Post-Op Placebo 2 (DRUG).
Who is sponsoring clinical trial NCT03652818?
This trial is sponsored by Nevakar, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03652818's enrollment target sits among peer trials
115 626th of 2000 higher than 1,374 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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