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NCT03644524 · ClinicalTrials.gov registry record · NA

Heat Therapy and Cardiometabolic Health in Obese Women

A NA study, sponsored by University of Oregon.

Completed
Registry status
NA
Development phase
20
Enrollment target

NCT03644524: Completed NA study, sponsored by University of Oregon.

NCT03644524 is a NA study that has completed, run by University of Oregon. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03644524, a NA study, has completed, sponsored by University of Oregon.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

Traditional medical treatments are often based on research done exclusively in males, and recent research efforts in the physiology community have highlighted critical sex differences in disease presentation and progression. For example, the relative risk of fatal heart disease is 50% greater in obese, diabetic women as compared to their male counterparts, and women appear to respond differently to lifestyle interventions such as exercise compared with men. Chronic passive heat exposure (hot tub use) provides alternative or supplemental therapeutic potential for improving cardiovascular and metabolic health in obese women. In addition, passive heat exposure may offer specific cellular protection from stresses like a lack of blood flow (ischemia), which is the primary cause of fatal coronary heart disease. This study is investigating the possible cardiovascular and metabolic health benefits of chronic passive heat exposure, and whether regular hot tub use (3-4 days per week for 8-10 weeks) may reduce obese womens' cardiometabolic risk. The investigators are examining cardiovascular health through blood pressure, blood vessel stiffness, sympathetic ('fight or flight') activity, and responsiveness to stresses like increased or decreased blood flow. The investigators are also examining metabolic health through an oral glucose tolerance test and a subcutaneous fat biopsy. The goal of this research is to develop a therapy targeted toward the specific health needs and complications of obese women, in an effort to improve cardiovascular and metabolic health and provide therapeutic alternatives in this high-risk population.

Primary Outcome

Resting supine blood pressure, measured in triplicate with median recorded

Interventions

  • BEHAVIORAL Heat therapy

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2015-09-08
Est. Completion 2018-07-01
Phase NA
University of Oregon

63 total trials

What the finished NCT03644524 record still lists

NCT03644524 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Heat therapy is the first listed.

NCT03644524 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03644524 about?

NCT03644524 is a clinical study titled "Heat Therapy and Cardiometabolic Health in Obese Women". Traditional medical treatments are often based on research done exclusively in males, and recent research efforts in the physiology community have highlighted critical sex differences in disease presentation and progression. For example, the relative risk of fatal heart disease is 50% greater in obe...

What is the current status of trial NCT03644524?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2015-09-08. Estimated completion is 2018-07-01.

What interventions are being tested in trial NCT03644524?

The interventions under investigation include: Heat therapy (BEHAVIORAL).

Who is sponsoring clinical trial NCT03644524?

This trial is sponsored by University of Oregon, which has 63 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03644524's enrollment target sits among peer trials

20 1768th of 2000 higher than 140 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03644524, the US trial registry maintained by the National Library of Medicine. NCT03644524 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.