Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03637972 · ClinicalTrials.gov registry record · Phase 3
COMET2 Project 1 Filter Ventilation Study
A Phase 3 study, sponsored by Masonic Cancer Center, University of Minnesota.
- Completed
- Registry status
- Phase 3
- Development phase
- 118
- Enrollment target
NCT03637972: Completed Phase 3 study, sponsored by Masonic Cancer Center, University of Minnesota.
NCT03637972 is a Phase 3 study that has completed, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 118 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03637972, a Phase 3 study, has completed, sponsored by Masonic Cancer Center, University of Minnesota.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 118 participants
- Enrollment target
Study Summary
Phase III randomized, 2 x 2 design, open label, multi-center study that will assess the removal of filter ventilation on smoking behavior and biomarkers in a tobacco and nicotine product marketplace simulation of a real world environment.
Primary Outcome
The total NNAL at the 8 week visit of Phase 3 adjusted for NNAL at baseline (Phase 2, week 00)
Interventions
- OTHER Ventilated cigarettes only
- OTHER Unventilated cigarettes only
- OTHER Access to Experimental Marketplace: Ventilated cigarettes + alternative nicotine delivery systems
- OTHER Access to Experimental Marketplace: Unventilated cigarettes + ANDS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 118 participants |
| Start Date | 2018-10-18 |
| Est. Completion | 2021-12-09 |
| Phase | Phase 3 |
What the finished NCT03637972 record still lists
NCT03637972 is an interventional study that assigns participants to a tested intervention. The registered 118 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 4 interventions - of which Ventilated cigarettes only is the first listed.
NCT03637972 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03637972 about?
NCT03637972 is a clinical study titled "COMET2 Project 1 Filter Ventilation Study". Phase III randomized, 2 x 2 design, open label, multi-center study that will assess the removal of filter ventilation on smoking behavior and biomarkers in a tobacco and nicotine product marketplace simulation of a real world environment.
What is the current status of trial NCT03637972?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 118 participants. The study started on 2018-10-18. Estimated completion is 2021-12-09.
What interventions are being tested in trial NCT03637972?
The interventions under investigation include: Ventilated cigarettes only (OTHER), Unventilated cigarettes only (OTHER), Access to Experimental Marketplace: Ventilated cigarettes + alternative nicotine delivery systems (OTHER), Access to Experimental Marketplace: Unventilated cigarettes + ANDS (OTHER).
Who is sponsoring clinical trial NCT03637972?
This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03637972's enrollment target sits among peer trials
118 1641st of 2000 higher than 359 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03821623 · 118 participants · Phase 2
Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
- NCT04040959 · 118 participants · Phase 2
Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD
- NCT04696029 · 118 participants · Phase 2
DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma
- NCT05223192 · 118 participants · NA
The Effects of Entrainment on Respiratory Stability and Cerebral Oxygenation in Preterm Infants
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI