Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03635450 · ClinicalTrials.gov registry record · Phase 1

Study of hCT-MSC in Newborn Infants With Moderate or Severe HIE

A Phase 1 study, sponsored by Joanne Kurtzberg, MD.

Completed
Registry status
Phase 1
Development phase
6
Enrollment target

NCT03635450: Completed Phase 1 study, sponsored by Joanne Kurtzberg, MD.

NCT03635450 is a Phase 1 study that has completed, run by Joanne Kurtzberg, MD. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03635450, a Phase 1 study, has completed, sponsored by Joanne Kurtzberg, MD.

COMPLETED
Registry status
Phase 1
Development phase
6 participants
Enrollment target

Study Summary

To determine the safety of single and repeated intravenous doses of hCT-MSC in newborn infants with HIE.

Primary Outcome

for this study, infusion reactions are defined as anaphylactic or anaphylactoid reactions with clinical signs inclusive of skin rashes, bronchospasm, angioedema, myocardial infarcts, arrhythmias, and acute lung injury.

Interventions

  • BIOLOGICAL Infusion of hCT-MSC

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2018-12-27
Est. Completion 2020-12-28
Phase Phase 1
Joanne Kurtzberg, MD

15 total trials

What the finished NCT03635450 record still lists

NCT03635450 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which Infusion of hCT-MSC is the first listed.

NCT03635450 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03635450 about?

NCT03635450 is a clinical study titled "Study of hCT-MSC in Newborn Infants With Moderate or Severe HIE". To determine the safety of single and repeated intravenous doses of hCT-MSC in newborn infants with HIE.

What is the current status of trial NCT03635450?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2018-12-27. Estimated completion is 2020-12-28.

What interventions are being tested in trial NCT03635450?

The interventions under investigation include: Infusion of hCT-MSC (BIOLOGICAL).

Who is sponsoring clinical trial NCT03635450?

This trial is sponsored by Joanne Kurtzberg, MD, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03635450's enrollment target sits among peer trials

6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03635450, the US trial registry maintained by the National Library of Medicine. NCT03635450 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.