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NCT03631680 · ClinicalTrials.gov registry record
The Role of Estrogen in Adipocyte Remodeling Following Surgical Menopause
A clinical trial, sponsored by Pennington Biomedical Research Center.
- Terminated
- Registry status
- 2
- Enrollment target
NCT03631680 is a clinical trial that was terminated before completion, run by Pennington Biomedical Research Center. The registered enrollment target is 2 participants.
The verdict
NCT03631680 was terminated before completion, sponsored by Pennington Biomedical Research Center.
- TERMINATED
- Registry status
- 2 participants
- Enrollment target
Study Summary
The overarching aim of this study is to assess the downstream effects of abrupt estrogen deficiency in women undergoing elective bilateral oophorectomy by studying: 1. the rate of in vivo adipogenesis in the subcutaneous abdominal (scABD) and subcutaneous femoral (scFEM) adipose tissue depots following bilateral oophorectomy surgery using an innovative (and tested) 8-week incorporation of stable isotope (deuterium; 2H) administered in the form of heavy water (2H2O) to endogenously label adipose tissue DNA; 2. the changes in expression of subcutaneous adipose tissue genes and proteins specific to adipocyte expansion and function; extracellular matrix remodeling and fibrosis; and inflammation in the scABD and scFEM depots before and after elective bilateral oophorectomy.
Interventions
- PROCEDURE Bilateral Oophorectomy Surgery
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2018-09-25 |
| Est. Completion | 2022-11-11 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03631680
The ClinicalTrials.gov registry entry for NCT03631680 describes a study currently listed as terminated, categorized as an unspecified phase. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pennington Biomedical Research Center, which has 258 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Bilateral Oophorectomy Surgery is the first listed.
NCT03631680 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03631680 about?
NCT03631680 is a clinical study titled "The Role of Estrogen in Adipocyte Remodeling Following Surgical Menopause". The overarching aim of this study is to assess the downstream effects of abrupt estrogen deficiency in women undergoing elective bilateral oophorectomy by studying: 1. the rate of in vivo adipogenesis in the subcutaneous abdominal (scABD) and subcutaneous femoral (scFEM) adipose tissue depots follo...
What is the current status of trial NCT03631680?
This trial is currently terminated. The enrollment target is 2 participants. The study started on 2018-09-25. Estimated completion is 2022-11-11.
What interventions are being tested in trial NCT03631680?
The interventions under investigation include: Bilateral Oophorectomy Surgery (PROCEDURE).
Who is sponsoring clinical trial NCT03631680?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
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