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NCT03626246 · ClinicalTrials.gov registry record
Pathogenesis of Compromised Bone Quality and Mechanics in Chronic Kidney Disease
A clinical trial, sponsored by Columbia University.
- Completed
- Registry status
- 50
- Enrollment target
NCT03626246: Completed study, sponsored by Columbia University.
NCT03626246 is a clinical trial that has completed, run by Columbia University. The registered enrollment target is 50 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03626246 has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
Study Summary
Kidney disease patients have a variety of bone disorders that result in bone loss and fractures. The mechanisms of these bone disorders are not clear but may be related to abnormal modification of a bone protein known as collagen. Therefore, the investigators are conducting this research study to identify underlying mechanisms that are responsible for the disruption of bone collagen and determining whether the abnormal bone collagen impairs bone strength. The investigators intend to identify these mechanisms through studying relationships between kidney disease and bone strength via bone imaging, bone biopsy and non-invasive measures from blood and skin.
Primary Outcome
In patients with CKD stage 3-5, the investigators will obtain transiliac crest bone biopsies and determine the amount of advanced glycation end-products that are present in bone collagen
Interventions
- OTHER Kidney disease
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2016-07-01 |
| Est. Completion | 2020-02-28 |
What the finished NCT03626246 record still lists
NCT03626246 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Kidney disease is the first listed.
NCT03626246 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03626246 about?
NCT03626246 is a clinical study titled "Pathogenesis of Compromised Bone Quality and Mechanics in Chronic Kidney Disease". Kidney disease patients have a variety of bone disorders that result in bone loss and fractures. The mechanisms of these bone disorders are not clear but may be related to abnormal modification of a bone protein known as collagen. Therefore, the investigators are conducting this research study to id...
What is the current status of trial NCT03626246?
This trial is currently completed. The enrollment target is 50 participants. The study started on 2016-07-01. Estimated completion is 2020-02-28.
What interventions are being tested in trial NCT03626246?
The interventions under investigation include: Kidney disease (OTHER).
Who is sponsoring clinical trial NCT03626246?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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