Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03613844 · ClinicalTrials.gov registry record · Phase 2
DHA Brain Delivery Trial
A Phase 2 study, sponsored by University of Southern California.
- Completed
- Registry status
- Phase 2
- Development phase
- 365
- Enrollment target
NCT03613844: Completed Phase 2 study, sponsored by University of Southern California.
NCT03613844 is a Phase 2 study that has completed, run by University of Southern California. The registered enrollment target is 365 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (174% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03613844, a Phase 2 study, has completed, sponsored by University of Southern California.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 365 participants
- Enrollment target
Study Summary
Carrying the APOE ɛ4 allele is the strongest genetic risk factor for developing Alzheimer's disease. The goal of this project is to identify whether carrying the APOE ɛ4 allele is associated with reduced delivery of DHA to the brain. This information will help us identify the target population that could benefit from DHA supplementation to prevent cognitive decline.
Primary Outcome
cerebrospinal fluid fatty acids assessed by mass spectrometry
Interventions
- DRUG Placebo
- DRUG DHA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 365 participants |
| Start Date | 2018-09-01 |
| Est. Completion | 2024-05-16 |
| Phase | Phase 2 |
What the finished NCT03613844 record still lists
NCT03613844 is an interventional study that assigns participants to a tested intervention. The registered 365 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (174% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03613844 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03613844 about?
NCT03613844 is a clinical study titled "DHA Brain Delivery Trial". Carrying the APOE ɛ4 allele is the strongest genetic risk factor for developing Alzheimer's disease. The goal of this project is to identify whether carrying the APOE ɛ4 allele is associated with reduced delivery of DHA to the brain. This information will help us identify the target population that ...
What is the current status of trial NCT03613844?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 365 participants. The study started on 2018-09-01. Estimated completion is 2024-05-16.
What interventions are being tested in trial NCT03613844?
The interventions under investigation include: Placebo (DRUG), DHA (DRUG).
Who is sponsoring clinical trial NCT03613844?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03613844's enrollment target sits among peer trials
365 121st of 2000 higher than 1,880 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04049604 · 365 participants · NA
IDENTIFY Study: Natural History of Maternal Neoplasia
- NCT05065840 · 365 participants · NA
Advancing HPV Vaccination Among HIV Positive Adults: The CHAMPS Study
- NCT05303519 · 365 participants · Phase 3
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
- NCT05592626 · 365 participants · Phase 1
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI