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NCT03603899 · ClinicalTrials.gov registry record · Phase 1
Hp129 Xenon Imaging and BOS in Lung Transplantation
A Phase 1 study of Bronchiolitis Obliterans, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- Phase 1
- Development phase
- 3
- Enrollment target
- 1
- Study location
NCT03603899 is a Phase 1 study of Bronchiolitis Obliterans that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 3 participants, below the 409-participant average among 9 other Bronchiolitis Obliterans trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT03603899, a Phase 1 study of Bronchiolitis Obliterans, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 3 participants
- Enrollment target
- 1
- Study location
Study Summary
The research is being conducted to develop new imaging methods that are sufficiently sensitive to allow for early diagnosis of BOS, a chronic allograft rejection affecting 50-60% of lung transplanted recipients who survive 5 years after transplant. Although lung transplantation has evolved into an effective therapeutic option for a large number of pediatric patients with end-stage pulmonary disease, long-term survival after lung transplantation is far worse than after the transplantation of other solid organs. This research may improve patient outcomes through earlier diagnosis of changes leading to BOS by obtaining image guided research biopsies of transplanted lung. Biopsies may be used for future research of ex vivo biomarkers of BOS and in the development of treatments through future clinical trials.
Conditions Studied
Interventions
- DRUG Hp 129Xenon
Study Locations (1)
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2020-09-09 |
| Est. Completion | 2024-05-28 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03603899
The ClinicalTrials.gov registry entry for NCT03603899 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 409-participant average among 9 other Bronchiolitis Obliterans trials with a reported enrollment target (99% lower). The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Bronchiolitis Obliterans appearing as the primary indexed condition, and to 1 intervention - of which Hp 129Xenon is the first listed.
NCT03603899 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT03603899 about?
NCT03603899 is a clinical study titled "Hp129 Xenon Imaging and BOS in Lung Transplantation". The research is being conducted to develop new imaging methods that are sufficiently sensitive to allow for early diagnosis of BOS, a chronic allograft rejection affecting 50-60% of lung transplanted recipients who survive 5 years after transplant. Although lung transplantation has evolved into an e...
What is the current status of trial NCT03603899?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2020-09-09. Estimated completion is 2024-05-28.
What conditions does trial NCT03603899 study?
This clinical trial studies the following conditions: Bronchiolitis Obliterans.
What interventions are being tested in trial NCT03603899?
The interventions under investigation include: Hp 129Xenon (DRUG).
Who is sponsoring clinical trial NCT03603899?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03603899 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.