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NCT03599089 · ClinicalTrials.gov registry record · Phase 2
Study of CA-008 (Vocacapsaicin) in Bunionectomy Patients
A Phase 2 study, sponsored by Concentric Analgesics.
- Completed
- Registry status
- Phase 2
- Development phase
- 147
- Enrollment target
NCT03599089: Completed Phase 2 study, sponsored by Concentric Analgesics.
NCT03599089 is a Phase 2 study that has completed, run by Concentric Analgesics. The registered enrollment target is 147 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (11% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03599089, a Phase 2 study, has completed, sponsored by Concentric Analgesics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 147 participants
- Enrollment target
Study Summary
This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study evaluating a single dose of one of three CA-008 dose levels vs. placebo injected during an elective bunionectomy Bunionectomy to assess post-surgical pain management and the need for rescue medication (oxycodone).
Primary Outcome
Mean area under the curve (AUC) of the Numeric Rating Scale (NRS) weighted sum of pain intensity scores (at rest) from 0-10 where 0 is no pain and 10 is the worst pain imaginable for CA-008 compared to placebo. The time was collected 0 to 96 hours post-dose
Interventions
- DRUG Placebo
- DRUG Acetaminophen
- DRUG Ketorolac
- DRUG Oxycodone
- DRUG CA-008
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 147 participants |
| Start Date | 2018-07-09 |
| Est. Completion | 2018-10-23 |
| Phase | Phase 2 |
What the finished NCT03599089 record still lists
NCT03599089 is an interventional study that assigns participants to a tested intervention. The registered 147 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (11% higher).
The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.
NCT03599089 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03599089 about?
NCT03599089 is a clinical study titled "Study of CA-008 (Vocacapsaicin) in Bunionectomy Patients". This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study evaluating a single dose of one of three CA-008 dose levels vs. placebo injected during an elective bunionectomy Bunionectomy to assess post-surgical pain management and the need for rescue medicatio...
What is the current status of trial NCT03599089?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 147 participants. The study started on 2018-07-09. Estimated completion is 2018-10-23.
What interventions are being tested in trial NCT03599089?
The interventions under investigation include: Placebo (DRUG), Acetaminophen (DRUG), Ketorolac (DRUG), Oxycodone (DRUG), CA-008 (DRUG).
Who is sponsoring clinical trial NCT03599089?
This trial is sponsored by Concentric Analgesics, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03599089's enrollment target sits among peer trials
147 495th of 2000 higher than 1,505 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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