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NCT03593785 · ClinicalTrials.gov registry record · Phase 1

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD8233 in Healthy Male Subjects With Increased Elevated LDL-C Levels.

A Phase 1 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 1
Development phase
73
Enrollment target

NCT03593785 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 73 participants.

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The verdict

NCT03593785, a Phase 1 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 1
Development phase
73 participants
Enrollment target

Study Summary

AZD8233 has not been evaluated in clinical studies previously. This is a first-in-human (FiH) study. This study will assess the safety, tolerability and pharmacokinetics (PK) of AZD8233, following subcutaneous (SC) administration of single ascending dose (SAD) of AZD8233. This study will also investigate the pharmacodynamics (PD) of AZD8233 by investigating the effect of AZD8233 on levels of cholesterol and related biomarkers.

Interventions

  • DRUG AZD8233

Trial Details

FieldValue
Enrollment Target 73 participants
Start Date 2018-08-03
Est. Completion 2020-12-19
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT03593785

The ClinicalTrials.gov registry entry for NCT03593785 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 73 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which AZD8233 is the first listed.

NCT03593785 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03593785 about?

NCT03593785 is a clinical study titled "A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD8233 in Healthy Male Subjects With Increased Elevated LDL-C Levels.". AZD8233 has not been evaluated in clinical studies previously. This is a first-in-human (FiH) study. This study will assess the safety, tolerability and pharmacokinetics (PK) of AZD8233, following subcutaneous (SC) administration of single ascending dose (SAD) of AZD8233. This study will also invest...

What is the current status of trial NCT03593785?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 73 participants. The study started on 2018-08-03. Estimated completion is 2020-12-19.

What interventions are being tested in trial NCT03593785?

The interventions under investigation include: AZD8233 (DRUG).

Who is sponsoring clinical trial NCT03593785?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.