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NCT03593434 · ClinicalTrials.gov registry record
Airway Clearance Therapy on Hyperpolarized 129Xenon and MRI
A clinical trial, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- 20
- Enrollment target
NCT03593434: Completed study, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT03593434 is a clinical trial that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 20 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03593434 has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
Study Summary
This is an observational cohort study building on an existing protocol at our institution recruiting CF patients who are 6-21 years old with one or two copies of the F508del CFTR mutation. That existing protocol seeks to enroll a total of 38 subjects; it includes three to four (three scheduled, with a fourth optional) study visits, with spirometry, LCI, UTE MRI, and 129Xe MRI being performed at each visit. This present study will utilize existing study visits for the NHLBI study, with a sub-set of 20 subjects opting-in to have all of the procedures performed twice, with an intervening ACT, during one of their study visits.
Primary Outcome
Quantify the effect of ACT on 129Xe MRI in ventilation defect percentage (%), in 20 children ages 6-21 years with CF
Interventions
- DRUG hyperpolarized Xenon gas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2018-07-30 |
| Est. Completion | 2021-12-30 |
What the finished NCT03593434 record still lists
NCT03593434 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which hyperpolarized Xenon gas is the first listed.
NCT03593434 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03593434 about?
NCT03593434 is a clinical study titled "Airway Clearance Therapy on Hyperpolarized 129Xenon and MRI". This is an observational cohort study building on an existing protocol at our institution recruiting CF patients who are 6-21 years old with one or two copies of the F508del CFTR mutation. That existing protocol seeks to enroll a total of 38 subjects; it includes three to four (three scheduled, with...
What is the current status of trial NCT03593434?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2018-07-30. Estimated completion is 2021-12-30.
What interventions are being tested in trial NCT03593434?
The interventions under investigation include: hyperpolarized Xenon gas (DRUG).
Who is sponsoring clinical trial NCT03593434?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
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