Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03591861 · ClinicalTrials.gov registry record · NA
Therapeutic Targeting of Sex Differences in Pediatric Brain Tumor Glycolysis
A NA study, sponsored by Washington University School of Medicine.
- Terminated
- Registry status
- NA
- Development phase
- 2
- Enrollment target
NCT03591861: Clinical Trial NA study, sponsored by Washington University School of Medicine.
NCT03591861 is a NA study that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03591861, a NA study, was terminated before completion, sponsored by Washington University School of Medicine.
- TERMINATED
- Registry status
- NA
- Development phase
- 2 participants
- Enrollment target
Study Summary
The investigators will develop the concept of a sex-specific therapeutic intervention for gliomas that is based upon dietary carbohydrate restriction. The investigators will integrate metabolomics tools and FDG-PET imaging to validate the ketogenic diet on a sex-specific basis.
Primary Outcome
* The study will be defined as being feasible if all 15 patients can be recruited within 3 years * Please note that feasibility of the study is dependent on both primary outcome measures
Interventions
- DRUG BCNU
- PROCEDURE Ketogenic diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2019-05-01 |
| Est. Completion | 2022-11-01 |
| Phase | NA |
Why NCT03591861 stopped before completion
NCT03591861 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which BCNU is the first listed.
NCT03591861 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03591861 about?
NCT03591861 is a clinical study titled "Therapeutic Targeting of Sex Differences in Pediatric Brain Tumor Glycolysis". The investigators will develop the concept of a sex-specific therapeutic intervention for gliomas that is based upon dietary carbohydrate restriction. The investigators will integrate metabolomics tools and FDG-PET imaging to validate the ketogenic diet on a sex-specific basis.
What is the current status of trial NCT03591861?
This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2019-05-01. Estimated completion is 2022-11-01.
What interventions are being tested in trial NCT03591861?
The interventions under investigation include: BCNU (DRUG), Ketogenic diet (PROCEDURE).
Who is sponsoring clinical trial NCT03591861?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03591861's enrollment target sits among peer trials
2 1997th of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI