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NCT03590652 · ClinicalTrials.gov registry record · Phase 2

Daratumumab, Ixazomib, Pomalidomide, and Dexamethasone as Salvage Therapy in Relapsed/Refractory Multiple Myeloma

A Phase 2 study, sponsored by University of California, San Diego.

Terminated
Registry status
Phase 2
Development phase
23
Enrollment target

NCT03590652: Clinical Trial Phase 2 study, sponsored by University of California, San Diego.

NCT03590652 is a Phase 2 study that was terminated before completion, run by University of California, San Diego. The registered enrollment target is 23 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03590652, a Phase 2 study, was terminated before completion, sponsored by University of California, San Diego.

TERMINATED
Registry status
Phase 2
Development phase
23 participants
Enrollment target

Study Summary

The purpose of this study is to determine the overall response rate of patients with Multiple Myeloma to the combination of Daratumumab, Ixazomib, Pomalidomide and Dexamethasone.

Primary Outcome

Anti-cancer response as defined by the International Uniform Response Criteria Consensus Recommendations

Interventions

  • DRUG Dexamethasone
  • DRUG Pomalidomide
  • DRUG Ixazomib
  • DRUG Daratumumab-Hyaluronidase-Fihj@1,800 Mg-30,000 Unit/15 mL@SUBCUT@VIAL (ML)

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2018-10-17
Est. Completion 2025-07-02
Phase Phase 2
University of California, San Diego

775 total trials

Why NCT03590652 stopped before completion

NCT03590652 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 4 interventions - of which Dexamethasone is the first listed.

NCT03590652 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03590652 about?

NCT03590652 is a clinical study titled "Daratumumab, Ixazomib, Pomalidomide, and Dexamethasone as Salvage Therapy in Relapsed/Refractory Multiple Myeloma". The purpose of this study is to determine the overall response rate of patients with Multiple Myeloma to the combination of Daratumumab, Ixazomib, Pomalidomide and Dexamethasone.

What is the current status of trial NCT03590652?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2018-10-17. Estimated completion is 2025-07-02.

What interventions are being tested in trial NCT03590652?

The interventions under investigation include: Dexamethasone (DRUG), Pomalidomide (DRUG), Ixazomib (DRUG), Daratumumab-Hyaluronidase-Fihj@1,800 Mg-30,000 Unit/15 mL@SUBCUT@VIAL (ML) (DRUG).

Who is sponsoring clinical trial NCT03590652?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03590652's enrollment target sits among peer trials

23 1784th of 2000 higher than 211 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03590652, the US trial registry maintained by the National Library of Medicine. NCT03590652 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.