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NCT03584425 · ClinicalTrials.gov registry record · Early Phase 1
Imaging Laterality in Chronic Stroke Patients
A Early Phase 1 study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 44
- Enrollment target
NCT03584425 is a Early Phase 1 study that has completed, run by Medical University of South Carolina. The registered enrollment target is 44 participants.
The verdict
NCT03584425, a Early Phase 1 study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 44 participants
- Enrollment target
Study Summary
In healthy individuals, unimanual movement (with either the left or right hand) is associated with activity in a network of predominantly contralateral brain regions, including the primary motor cortex (PMC). This laterality is often compromised following a middle cerebral artery (MCA) stroke. Neuroimaging studies of these patients have shown that unimanual movements with the effected hand are associated with elevated Blood Oxygen-Level Dependent (BOLD) signal in both the lesioned and the nonlesioned primary motor cortices. Elevated activity in the contralesional PMC is well-established in chronic stroke patients and is associated with poor motor rehabilitation outcomes. Yet the neurobiologic basis for this aberrant neural activity is equivocal. The overarching goal of this project is to determine the neurobiologic basis for elevated activity in the contralesional primary motor cortex.
Interventions
- DIAGNOSTIC_TEST Rasch modified version of the Fugl-Meyer Motor assessment
- DIAGNOSTIC_TEST Anatomical image acquisition
- DIAGNOSTIC_TEST Functional MRI task and acquisition
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2014-12-15 |
| Est. Completion | 2019-05-30 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03584425
The ClinicalTrials.gov registry entry for NCT03584425 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Rasch modified version of the Fugl-Meyer Motor assessment is the first listed.
NCT03584425 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03584425 about?
NCT03584425 is a clinical study titled "Imaging Laterality in Chronic Stroke Patients". In healthy individuals, unimanual movement (with either the left or right hand) is associated with activity in a network of predominantly contralateral brain regions, including the primary motor cortex (PMC). This laterality is often compromised following a middle cerebral artery (MCA) stroke. Neuro...
What is the current status of trial NCT03584425?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 44 participants. The study started on 2014-12-15. Estimated completion is 2019-05-30.
What interventions are being tested in trial NCT03584425?
The interventions under investigation include: Rasch modified version of the Fugl-Meyer Motor assessment (DIAGNOSTIC_TEST), Anatomical image acquisition (DIAGNOSTIC_TEST), Functional MRI task and acquisition (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03584425?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
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