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NCT03579589 · ClinicalTrials.gov registry record · Phase 1

The Effect of Sugammadex Versus Neostigmine During Neuromuscular Blockade Reversal

A Phase 1 study, sponsored by Ohio State University.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target

NCT03579589: Completed Phase 1 study, sponsored by Ohio State University.

NCT03579589 is a Phase 1 study that has completed, run by Ohio State University. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03579589, a Phase 1 study, has completed, sponsored by Ohio State University.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target

Study Summary

Patients who undergo surgery receive drugs called neuromuscular blocking agents (NMBA) that to block the activity of muscles. When the surgery is over, the block needs to be reversed. Suggammadex and neostigmine are examples of drugs that reverse blocks. This study aims to investigate if sugammadex is associated with a significantly reduced time to discharge from the operating room to the postoperative unit when compared to neostigmine.

Primary Outcome

Time from peritoneal closure (port sites) to anesthesia readiness for OR discharge to PACU

Interventions

  • DRUG Sugammadex vs Neostigmine

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2018-08-15
Est. Completion 2019-12-15
Phase Phase 1
Ohio State University

552 total trials

What the finished NCT03579589 record still lists

NCT03579589 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).

The record links to 0 conditions, and to 1 intervention - of which Sugammadex vs Neostigmine is the first listed.

NCT03579589 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03579589 about?

NCT03579589 is a clinical study titled "The Effect of Sugammadex Versus Neostigmine During Neuromuscular Blockade Reversal". Patients who undergo surgery receive drugs called neuromuscular blocking agents (NMBA) that to block the activity of muscles. When the surgery is over, the block needs to be reversed. Suggammadex and neostigmine are examples of drugs that reverse blocks. This study aims to investigate if sugammadex ...

What is the current status of trial NCT03579589?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2018-08-15. Estimated completion is 2019-12-15.

What interventions are being tested in trial NCT03579589?

The interventions under investigation include: Sugammadex vs Neostigmine (DRUG).

Who is sponsoring clinical trial NCT03579589?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03579589's enrollment target sits among peer trials

40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03579589, the US trial registry maintained by the National Library of Medicine. NCT03579589 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.