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NCT03574194 · ClinicalTrials.gov registry record · NA
Methionine-Restricted Diet to Potentiate The Effects of Radiation Therapy
A NA study, sponsored by West Virginia University.
- Terminated
- Registry status
- NA
- Development phase
- 8
- Enrollment target
NCT03574194: Clinical Trial NA study, sponsored by West Virginia University.
NCT03574194 is a NA study that was terminated before completion, run by West Virginia University. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03574194, a NA study, was terminated before completion, sponsored by West Virginia University.
- TERMINATED
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
Study Summary
A diet consisting of a reduced quantity of the essential amino acid methionine sensitizes cancer cells to radiation therapy and reduces metastasis formation and disease progression in mice. However, to date, dietary restriction of methionine has not been tested in combination with radiation therapy in humans as a strategy to improve patient outcomes.
Primary Outcome
The expected cumulative rate of grade 3-5 toxicity is less than 15%
Interventions
- DIETARY_SUPPLEMENT Methionine-restricted diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2018-06-12 |
| Est. Completion | 2021-12-31 |
| Phase | NA |
Why NCT03574194 stopped before completion
NCT03574194 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Methionine-restricted diet is the first listed.
NCT03574194 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03574194 about?
NCT03574194 is a clinical study titled "Methionine-Restricted Diet to Potentiate The Effects of Radiation Therapy". A diet consisting of a reduced quantity of the essential amino acid methionine sensitizes cancer cells to radiation therapy and reduces metastasis formation and disease progression in mice. However, to date, dietary restriction of methionine has not been tested in combination with radiation therapy ...
What is the current status of trial NCT03574194?
This trial is currently terminated. It is a NA study. The enrollment target is 8 participants. The study started on 2018-06-12. Estimated completion is 2021-12-31.
What interventions are being tested in trial NCT03574194?
The interventions under investigation include: Methionine-restricted diet (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03574194?
This trial is sponsored by West Virginia University, which has 122 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03574194's enrollment target sits among peer trials
8 1976th of 2000 higher than 19 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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