Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03572335 · ClinicalTrials.gov registry record
Systems Biology of Diffusion Impairment in Human Immunodeficiency Virus (HIV)
A clinical trial, sponsored by University of Pittsburgh.
- Completed
- Registry status
- 61
- Enrollment target
NCT03572335: Completed study, sponsored by University of Pittsburgh.
NCT03572335 is a clinical trial that has completed, run by University of Pittsburgh. The registered enrollment target is 61 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03572335 has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- 61 participants
- Enrollment target
Study Summary
Diffusing capacity for carbon monoxide (DLco) abnormalities are common in HIV+ individuals and associated with significant morbidity and mortality. The complexity and the individualized differences in causes of these abnormalities have been challenging to unravel using traditional approaches. In this proposal, the investigators construct a systems' modeling approach to identify novel molecular and clinical pathways contributing to DLco impairment in HIV+ individuals and to determine predictive signatures of DLco decline in order to develop strategies to treat and prevent abnormal lung function in this susceptible population.
Primary Outcome
elucidating complex associations and causal relationships between clinical characteristics, the host inflammatory response, cellular metabolism, the microbiome, and miRNAs.
Interventions
- DIAGNOSTIC_TEST PFT's (pulmonary function testing)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2018-09-06 |
| Est. Completion | 2024-08-01 |
What the finished NCT03572335 record still lists
NCT03572335 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 61 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which PFT's (pulmonary function testing) is the first listed.
NCT03572335 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03572335 about?
NCT03572335 is a clinical study titled "Systems Biology of Diffusion Impairment in Human Immunodeficiency Virus (HIV)". Diffusing capacity for carbon monoxide (DLco) abnormalities are common in HIV+ individuals and associated with significant morbidity and mortality. The complexity and the individualized differences in causes of these abnormalities have been challenging to unravel using traditional approaches. In thi...
What is the current status of trial NCT03572335?
This trial is currently completed. The enrollment target is 61 participants. The study started on 2018-09-06. Estimated completion is 2024-08-01.
What interventions are being tested in trial NCT03572335?
The interventions under investigation include: PFT's (pulmonary function testing) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03572335?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04115306 · 61 participants · Phase 1
Phase 1/1b/2 Study of Oral PMD-026 in Patients With Metastatic Breast Cancer
- NCT05070845 · 61 participants · Phase 2
Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia
- NCT05187832 · 61 participants · Phase 1
A Study of AND019 in Women With ER Positive HER2 Negative Advanced or Metastatic Breast Cancer
- NCT05269316 · 61 participants · Phase 1
Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI