Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03569085 · ClinicalTrials.gov registry record · Phase 1
Inhaled Anesthetics and Myocardial Strain
A Phase 1 study, sponsored by Kathirvel Subramaniam.
- Completed
- Registry status
- Phase 1
- Development phase
- 26
- Enrollment target
NCT03569085: Completed Phase 1 study, sponsored by Kathirvel Subramaniam.
NCT03569085 is a Phase 1 study that has completed, run by Kathirvel Subramaniam. The registered enrollment target is 26 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03569085, a Phase 1 study, has completed, sponsored by Kathirvel Subramaniam.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 26 participants
- Enrollment target
Study Summary
Speckle tracking imaging measuring software will be used for offline analysis of transesophageal echocardiogram (TEE) -acquired images of the left ventricle(LV) in four chambers(4C), two chambers (2C) and long axis (LAX) views to calculate global longitudinal strain (GLS) of LV for comparisons between sevoflurane and isoflurane at the same minimum alveolar concentration ( MAC) levels.
Primary Outcome
Global longitudinal Strain measures changes in longitudinal length of myocardium and is a unitless measure. TEE images will be taken during surgery, stored on central echocardiography server, then analyzed offline using a special software to calculate global longitudinal strain (GLS). GLS of LV will then be compared between isoflurane and sevoflurane at the same MAC concentrations.
Interventions
- DRUG Sevoflurane
- DRUG Isoflurane
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2018-06-27 |
| Est. Completion | 2023-05-04 |
| Phase | Phase 1 |
What the finished NCT03569085 record still lists
NCT03569085 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower).
The record links to 0 conditions, and to 2 interventions - of which Sevoflurane is the first listed.
NCT03569085 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03569085 about?
NCT03569085 is a clinical study titled "Inhaled Anesthetics and Myocardial Strain". Speckle tracking imaging measuring software will be used for offline analysis of transesophageal echocardiogram (TEE) -acquired images of the left ventricle(LV) in four chambers(4C), two chambers (2C) and long axis (LAX) views to calculate global longitudinal strain (GLS) of LV for comparisons betwe...
What is the current status of trial NCT03569085?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2018-06-27. Estimated completion is 2023-05-04.
What interventions are being tested in trial NCT03569085?
The interventions under investigation include: Sevoflurane (DRUG), Isoflurane (DRUG).
Who is sponsoring clinical trial NCT03569085?
This trial is sponsored by Kathirvel Subramaniam, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03569085's enrollment target sits among peer trials
26 1482nd of 2000 higher than 506 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02646475 · 26 participants · Phase 1
Metabolic Effects of Angiotensin-(1-7)
- NCT03603223 · 26 participants · Phase 2
Pembrolizumab in Treating Participants With Leukoplakia
- NCT04063592 · 26 participants · NA
AMI Construction in Lower Extremity Residual Limbs
- NCT04906460 · 26 participants · Phase 1
Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI