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NCT03567460 · ClinicalTrials.gov registry record · NA
Children and Adolescents With Marfan Syndrome: 10,000 Healthy Steps and Beyond
A NA study, sponsored by Stanford University.
- Completed
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT03567460: Completed NA study, sponsored by Stanford University.
NCT03567460 is a NA study that has completed, run by Stanford University. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03567460, a NA study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
Marfan patients are at risk of sudden death due to weakening of the wall of the large blood vessel leading from the heart (aorta). The wall of the aorta weakens and dilates which can rupture, leading to death, and sometimes during intense exercise. There is some evidence in Marfan patients that a stiffer aorta increases risk for rupture. For some time, clinical care has focused on what type of exercise these patients should avoid due to risk for aortic dissection. Little clinical emphasis has been placed on encouraging patients to engage in routine and safe exercise such as walking. Informed by this evidence, the investigators propose to collaboratively investigate whether regular exercise improves aortic health in adolescent Marfan patients.
Primary Outcome
The investigators' primary outcome measure is aortic stiffness measured by arterial tonometry (pulse wave velocity).
Interventions
- BEHAVIORAL Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2017-01-01 |
| Est. Completion | 2019-12-31 |
| Phase | NA |
What the finished NCT03567460 record still lists
NCT03567460 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Exercise is the first listed.
NCT03567460 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03567460 about?
NCT03567460 is a clinical study titled "Children and Adolescents With Marfan Syndrome: 10,000 Healthy Steps and Beyond". Marfan patients are at risk of sudden death due to weakening of the wall of the large blood vessel leading from the heart (aorta). The wall of the aorta weakens and dilates which can rupture, leading to death, and sometimes during intense exercise. There is some evidence in Marfan patients that a s...
What is the current status of trial NCT03567460?
This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2017-01-01. Estimated completion is 2019-12-31.
What interventions are being tested in trial NCT03567460?
The interventions under investigation include: Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT03567460?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03567460's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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