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NCT03565783 · ClinicalTrials.gov registry record · Phase 2

Cemiplimab in Treating Patients With Recurrent and Resectable Stage II-IV Head and Neck Cutaneous Squamous Cell Cancer Before Surgery

A Phase 2 study of Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck and Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, sponsored by M.D. Anderson Cancer Center.

Active
Registry status
Phase 2
Development phase
44
Enrollment target
1
Study location

NCT03565783 is a Phase 2 study of Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck and Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 44 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT03565783, a Phase 2 study of Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck and Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
44 participants
Enrollment target
1
Study location

Study Summary

This phase II trial studies how well cemiplimab works before surgery in treating patients with stage II-IV head and neck cutaneous squamous cell cancer that has come back (recurrent) and can be removed by surgery (resectable). Immunotherapy with monoclonal antibodies, such as cemiplimab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

Interventions

  • BIOLOGICAL Cemiplimab

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2018-07-03
Est. Completion 2027-12-31
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT03565783

The ClinicalTrials.gov registry entry for NCT03565783 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck appearing as the primary indexed condition, and to 1 intervention - of which Cemiplimab is the first listed.

NCT03565783 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT03565783 about?

NCT03565783 is a clinical study titled "Cemiplimab in Treating Patients With Recurrent and Resectable Stage II-IV Head and Neck Cutaneous Squamous Cell Cancer Before Surgery". This phase II trial studies how well cemiplimab works before surgery in treating patients with stage II-IV head and neck cutaneous squamous cell cancer that has come back (recurrent) and can be removed by surgery (resectable). Immunotherapy with monoclonal antibodies, such as cemiplimab, may help th...

What is the current status of trial NCT03565783?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2018-07-03. Estimated completion is 2027-12-31.

What conditions does trial NCT03565783 study?

This clinical trial studies the following conditions: Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck, Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck, Stage II Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8.

What interventions are being tested in trial NCT03565783?

The interventions under investigation include: Cemiplimab (BIOLOGICAL).

Who is sponsoring clinical trial NCT03565783?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03565783 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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