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NCT03565497 · ClinicalTrials.gov registry record · NA
Engaging Working Memory and Distress Tolerance to Aid Smoking Cessation
A NA study, sponsored by Boston University Charles River Campus.
- Terminated
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT03565497: Clinical Trial NA study, sponsored by Boston University Charles River Campus.
NCT03565497 is a NA study that was terminated before completion, run by Boston University Charles River Campus. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03565497, a NA study, was terminated before completion, sponsored by Boston University Charles River Campus.
- TERMINATED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
Specific Aims for this Project Are: 1. To evaluate the ability of two forms of mindfulness training, relative to a control intervention, to engage specific "triple-vulnerability" mechanistic targets that characterize low SES smokers. 1. The investigators hypothesize that both versions of the mindfulness training will show greater target engagement than the control treatment for mechanistic targets assessed under standard smoking conditions. 2. The investigators hypothesize that the enhanced mindfulness training, Mindfulness+IE, will show greater target engagement than the other two conditions for mechanistic targets assessed during the nicotine deprivation window. 2. To show that the hypothesized differential target engagement results in differential smoking self-control as evaluated by greater time to lapse, fewer cigarettes smoked, and different smoking topography in the McKee Lapse protocol. 3. To expand and refine the list of SOBC targets by showing the specific relationship between currently identified assays and empirically-validated alternative targets, with attention to showing which of the targeted mechanisms in which contexts are most linked to clinically-relevant outcomes assessed in the McKee protocol, and which offer redundant or non-significant prediction.
Primary Outcome
PANAS-State Negative was used to assess the mechanistic outcome of Negative Affectivity/Stress. Items from the negative subscale are summed to create a total score. Scores can range from 10-50, with lower scores representing lower levels of negative affect.
Interventions
- BEHAVIORAL Mindfulness Training
- BEHAVIORAL Wellness Education Control Condition
- BEHAVIORAL Mindfulness Training Plus IE
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2019-04-19 |
| Est. Completion | 2021-08-31 |
| Phase | NA |
Why NCT03565497 stopped before completion
NCT03565497 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 3 interventions - of which Mindfulness Training is the first listed.
NCT03565497 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03565497 about?
NCT03565497 is a clinical study titled "Engaging Working Memory and Distress Tolerance to Aid Smoking Cessation". Specific Aims for this Project Are: 1. To evaluate the ability of two forms of mindfulness training, relative to a control intervention, to engage specific "triple-vulnerability" mechanistic targets that characterize low SES smokers. 1. The investigators hypothesize that both versions of the mi...
What is the current status of trial NCT03565497?
This trial is currently terminated. It is a NA study. The enrollment target is 30 participants. The study started on 2019-04-19. Estimated completion is 2021-08-31.
What interventions are being tested in trial NCT03565497?
The interventions under investigation include: Mindfulness Training (BEHAVIORAL), Wellness Education Control Condition (BEHAVIORAL), Mindfulness Training Plus IE (BEHAVIORAL).
Who is sponsoring clinical trial NCT03565497?
This trial is sponsored by Boston University Charles River Campus, which has 104 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03565497's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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