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NCT03558152 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of UTTR1147A Compared With Placebo and With Vedolizumab in Participants With Moderate to Severe Ulcerative Colitis (UC)

A Phase 2 study, sponsored by Genentech.

Completed
Registry status
Phase 2
Development phase
195
Enrollment target

NCT03558152 is a Phase 2 study that has completed, run by Genentech. The registered enrollment target is 195 participants.

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The verdict

NCT03558152, a Phase 2 study, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 2
Development phase
195 participants
Enrollment target

Study Summary

This study is designed to evaluate the efficacy, safety, and pharmacokinetics of UTTR1147A compared with vedolizumab and with placebo in the treatment of participants with moderate to severe UC. This study will consist of two parts, Part A and Part B. Part A will test the induction of clinical remission and Part B will test the durability of clinical remission.

Interventions

  • DRUG Vedolizumab
  • DRUG UTTR1147A
  • DRUG UTTR1147A Placebo
  • DRUG Vedolizumab Placebo

Trial Details

FieldValue
Enrollment Target 195 participants
Start Date 2018-10-26
Est. Completion 2021-12-15
Phase Phase 2

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT03558152

The ClinicalTrials.gov registry entry for NCT03558152 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 195 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Vedolizumab is the first listed.

NCT03558152 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03558152 about?

NCT03558152 is a clinical study titled "A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of UTTR1147A Compared With Placebo and With Vedolizumab in Participants With Moderate to Severe Ulcerative Colitis (UC)". This study is designed to evaluate the efficacy, safety, and pharmacokinetics of UTTR1147A compared with vedolizumab and with placebo in the treatment of participants with moderate to severe UC. This study will consist of two parts, Part A and Part B. Part A will test the induction of clinical remis...

What is the current status of trial NCT03558152?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 195 participants. The study started on 2018-10-26. Estimated completion is 2021-12-15.

What interventions are being tested in trial NCT03558152?

The interventions under investigation include: Vedolizumab (DRUG), UTTR1147A (DRUG), UTTR1147A Placebo (DRUG), Vedolizumab Placebo (DRUG).

Who is sponsoring clinical trial NCT03558152?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.