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NCT03549468 · ClinicalTrials.gov registry record · NA
The Effect of Low LEVel TrAgus STimulation on the Electrophysiological Substrate of Patients With Ischemic CardioMyopathy Substrate of Subjects With Ischemic CardioMyopathy
A NA study, sponsored by University of Oklahoma.
- Completed
- Registry status
- NA
- Development phase
- 26
- Enrollment target
NCT03549468: Completed NA study, sponsored by University of Oklahoma.
NCT03549468 is a NA study that has completed, run by University of Oklahoma. The registered enrollment target is 26 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03549468, a NA study, has completed, sponsored by University of Oklahoma.
- COMPLETED
- Registry status
- NA
- Development phase
- 26 participants
- Enrollment target
Study Summary
Patients with ischemic cardiomyopathy (left ventricular ejection fraction \<35%) and heart failure who already have an implantable device with an atrial lead (dual chamber defibrillator or biventricular defibrillator) will undergo sequentially 1. Sham low level tragus stimulation (LLTS) (5min), 2. Active LLTS at 5Hz (15min) and 20Hz (15min) and 3. Active LLTS group with atrial pacing at 100bpm at 5Hz (15min) and 20Hz (15min). The latter is required to examine the effect of LLTS on RA independent of heart rate. Repolarization alternans will be measured by analyzing a regular 12-lead ECG using a custom-made software.
Primary Outcome
Repolarization alternans will be measured by analyzing a regular 12-lead ECG using a custom-made software
Interventions
- DEVICE Low level tragus stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2018-05-25 |
| Est. Completion | 2022-03-30 |
| Phase | NA |
What the finished NCT03549468 record still lists
NCT03549468 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Low level tragus stimulation is the first listed.
NCT03549468 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03549468 about?
NCT03549468 is a clinical study titled "The Effect of Low LEVel TrAgus STimulation on the Electrophysiological Substrate of Patients With Ischemic CardioMyopathy Substrate of Subjects With Ischemic CardioMyopathy". Patients with ischemic cardiomyopathy (left ventricular ejection fraction \<35%) and heart failure who already have an implantable device with an atrial lead (dual chamber defibrillator or biventricular defibrillator) will undergo sequentially 1. Sham low level tragus stimulation (LLTS) (5min), 2. A...
What is the current status of trial NCT03549468?
This trial is currently completed. It is a NA study. The enrollment target is 26 participants. The study started on 2018-05-25. Estimated completion is 2022-03-30.
What interventions are being tested in trial NCT03549468?
The interventions under investigation include: Low level tragus stimulation (DEVICE).
Who is sponsoring clinical trial NCT03549468?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03549468's enrollment target sits among peer trials
26 1710th of 2000 higher than 289 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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