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NCT03544632 · ClinicalTrials.gov registry record · Phase 2
Acellular Adipose Tissue (AAT) for Soft Tissue Reconstruction
A Phase 2 study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
NCT03544632: Completed Phase 2 study, sponsored by Johns Hopkins University.
NCT03544632 is a Phase 2 study that has completed, run by Johns Hopkins University. The registered enrollment target is 15 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03544632, a Phase 2 study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
Study Summary
Although other methods (e.g., autologous fat transfer, dermal-/collagen-based fillers) for soft tissue reconstruction exist, each has distinct disadvantages leaving room for improvement in this treatment area. Investigators in the Elisseeff Laboratory (Johns Hopkins University Department of Biomedical Engineering) have recently generated a novel tissue-derived material to create instructive matrices for soft tissue reconstruction called Acellular Adipose Tissue (AAT). This material takes advantage of the inherent bioactivity and unique mechanical properties of subcutaneous adipose tissue. Investigators' preclinical data suggest that AAT is safe for use in small and large animals; investigators' clinical (Phase I) data suggest that AAT is safe for use in humans. These data indicate that a Phase II, dose-escalation study of AAT's safety and efficacy in human subjects is warranted.
Interventions
- DRUG Acellular Adipose Tissue (AAT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2018-06-21 |
| Est. Completion | 2026-02-28 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03544632
The ClinicalTrials.gov registry entry for NCT03544632 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Acellular Adipose Tissue (AAT) is the first listed.
NCT03544632 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03544632 about?
NCT03544632 is a clinical study titled "Acellular Adipose Tissue (AAT) for Soft Tissue Reconstruction". Although other methods (e.g., autologous fat transfer, dermal-/collagen-based fillers) for soft tissue reconstruction exist, each has distinct disadvantages leaving room for improvement in this treatment area. Investigators in the Elisseeff Laboratory (Johns Hopkins University Department of Biomedic...
What is the current status of trial NCT03544632?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2018-06-21. Estimated completion is 2026-02-28.
What interventions are being tested in trial NCT03544632?
The interventions under investigation include: Acellular Adipose Tissue (AAT) (DRUG).
Who is sponsoring clinical trial NCT03544632?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
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