Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03538028 · ClinicalTrials.gov registry record · Phase 1
A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies
A Phase 1 study, sponsored by Incyte Biosciences International Sàrl.
- Completed
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
NCT03538028: Completed Phase 1 study, sponsored by Incyte Biosciences International Sàrl.
NCT03538028 is a Phase 1 study that has completed, run by Incyte Biosciences International Sàrl. The registered enrollment target is 22 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03538028, a Phase 1 study, has completed, sponsored by Incyte Biosciences International Sàrl.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02385 in participants with advanced malignancies.
Primary Outcome
TEAE defined as adverse events reported for the first time or worsening of a pre-existing event after first dose of study drug.
Interventions
- BIOLOGICAL INCAGN02385
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2018-06-18 |
| Est. Completion | 2020-10-07 |
| Phase | Phase 1 |
What the finished NCT03538028 record still lists
NCT03538028 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower).
The record links to 0 conditions, and to 1 intervention - of which INCAGN02385 is the first listed.
NCT03538028 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03538028 about?
NCT03538028 is a clinical study titled "A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies". The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02385 in participants with advanced malignancies.
What is the current status of trial NCT03538028?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2018-06-18. Estimated completion is 2020-10-07.
What interventions are being tested in trial NCT03538028?
The interventions under investigation include: INCAGN02385 (BIOLOGICAL).
Who is sponsoring clinical trial NCT03538028?
This trial is sponsored by Incyte Biosciences International Sàrl, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03538028's enrollment target sits among peer trials
22 1601st of 2000 higher than 386 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02508038 · 22 participants · Phase 1
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
- NCT03099356 · 22 participants · Phase 2
Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer
- NCT03676647 · 22 participants
Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules
- NCT04569591 · 22 participants · NA
DDAVP for Pituitary Adenoma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI