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NCT03537898 · ClinicalTrials.gov registry record · NA
Balanced Solutions and Plasma Electrolytes
A NA study, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 2,093
- Enrollment target
NCT03537898: Completed NA study, sponsored by Vanderbilt University Medical Center.
NCT03537898 is a NA study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 2,093 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (49% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03537898, a NA study, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,093 participants
- Enrollment target
Study Summary
The administration of intravenous fluids is ubiquitous in the care of the critically ill. Commonly available isotonic crystalloid solutions contain a broad spectrum electrolyte compositions including a range chloride concentrations. Recent prospective, randomized trials have shown improved patient outcomes with the use of balanced crystalloids compared to saline. There have not been large randomized studies comparing acetate buffered balanced crystalloids to non-acetate buffered balanced crystalloids in the critically ill. BASE will be a pilot study for a large, cluster-randomized, multiple-crossover trial enrolling critically ill patients from the Medical ICU at Vanderbilt University from June 2018 until January 2019. The primary endpoint will be plasma bicarbonate concentration between Intensive Care Unit admission and hospital discharge.
Primary Outcome
The primary outcome is a repeated measures variable of plasma bicarbonate concentration (mmol/L) between ICU admission and 7 days.
Interventions
- OTHER Lactated Ringer's
- OTHER Normosol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,093 participants |
| Start Date | 2018-06-01 |
| Est. Completion | 2019-03-02 |
| Phase | NA |
What the finished NCT03537898 record still lists
NCT03537898 is an interventional study that assigns participants to a tested intervention. Its 2,093 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (49% higher).
The record links to 0 conditions, and to 2 interventions - of which Lactated Ringer's is the first listed.
NCT03537898 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03537898 about?
NCT03537898 is a clinical study titled "Balanced Solutions and Plasma Electrolytes". The administration of intravenous fluids is ubiquitous in the care of the critically ill. Commonly available isotonic crystalloid solutions contain a broad spectrum electrolyte compositions including a range chloride concentrations. Recent prospective, randomized trials have shown improved patient o...
What is the current status of trial NCT03537898?
This trial is currently completed. It is a NA study. The enrollment target is 2,093 participants. The study started on 2018-06-01. Estimated completion is 2019-03-02.
What interventions are being tested in trial NCT03537898?
The interventions under investigation include: Lactated Ringer's (OTHER), Normosol (OTHER).
Who is sponsoring clinical trial NCT03537898?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03537898's enrollment target sits among peer trials
2,093 50th of 2000 higher than 1,951 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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