Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03537144 · ClinicalTrials.gov registry record · Phase 3
Acetaminophen vs Indomethacin in Treating hsPDA
A Phase 3 study, sponsored by University of Tennessee.
- Terminated
- Registry status
- Phase 3
- Development phase
- 37
- Enrollment target
NCT03537144: Clinical Trial Phase 3 study, sponsored by University of Tennessee.
NCT03537144 is a Phase 3 study that was terminated before completion, run by University of Tennessee. The registered enrollment target is 37 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03537144, a Phase 3 study, was terminated before completion, sponsored by University of Tennessee.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 37 participants
- Enrollment target
Study Summary
The purpose of this study is to see if acetaminophen (Tylenol) is as effective as indomethacin in closing patent ductus arteriosus in premature infants.
Primary Outcome
Definition of successful treatment of PDA is the PDA no longer meets the echocardiogram inclusion criteria.
Interventions
- DRUG Acetaminophen
- DRUG Indomethacin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2016-06 |
| Est. Completion | 2018-09 |
| Phase | Phase 3 |
Why NCT03537144 stopped before completion
NCT03537144 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which Acetaminophen is the first listed.
NCT03537144 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03537144 about?
NCT03537144 is a clinical study titled "Acetaminophen vs Indomethacin in Treating hsPDA". The purpose of this study is to see if acetaminophen (Tylenol) is as effective as indomethacin in closing patent ductus arteriosus in premature infants.
What is the current status of trial NCT03537144?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 37 participants. The study started on 2016-06. Estimated completion is 2018-09.
What interventions are being tested in trial NCT03537144?
The interventions under investigation include: Acetaminophen (DRUG), Indomethacin (DRUG).
Who is sponsoring clinical trial NCT03537144?
This trial is sponsored by University of Tennessee, which has 96 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03537144's enrollment target sits among peer trials
37 1901st of 2000 higher than 100 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02800486 · 37 participants · Phase 2
Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA
- NCT03173937 · 37 participants · Phase 1
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome
- NCT03295227 · 37 participants · Phase 1
Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic Cancer
- NCT03401047 · 37 participants · Early Phase 1
Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia