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NCT03536728 · ClinicalTrials.gov registry record · Phase 1
Oral AMXT 1501 Dicaprate in Combination With DFMO
A Phase 1 study, sponsored by Aminex Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 56
- Enrollment target
NCT03536728: Completed Phase 1 study, sponsored by Aminex Therapeutics.
NCT03536728 is a Phase 1 study that has completed, run by Aminex Therapeutics. The registered enrollment target is 56 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03536728, a Phase 1 study, has completed, sponsored by Aminex Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 56 participants
- Enrollment target
Study Summary
A Phase 1 study will be conducted to establish safety and dose level of AMXT 1501 dicaprate alone, and in combination with DFMO, in cancer patients.
Primary Outcome
To evaluate dose-limiting toxicities (DLTs) of AMXT 1501 in combination with DFMO, in patients with advanced cancer and to establish a recommended Phase 2 dose (RP2D)
Interventions
- DRUG DFMO
- DRUG AMXT1501
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2018-06-12 |
| Est. Completion | 2023-04-21 |
| Phase | Phase 1 |
What the finished NCT03536728 record still lists
NCT03536728 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which DFMO is the first listed.
NCT03536728 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03536728 about?
NCT03536728 is a clinical study titled "Oral AMXT 1501 Dicaprate in Combination With DFMO". A Phase 1 study will be conducted to establish safety and dose level of AMXT 1501 dicaprate alone, and in combination with DFMO, in cancer patients.
What is the current status of trial NCT03536728?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 56 participants. The study started on 2018-06-12. Estimated completion is 2023-04-21.
What interventions are being tested in trial NCT03536728?
The interventions under investigation include: DFMO (DRUG), AMXT1501 (DRUG).
Who is sponsoring clinical trial NCT03536728?
This trial is sponsored by Aminex Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03536728's enrollment target sits among peer trials
56 902nd of 2000 higher than 1,083 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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